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    BIOMARKER:

    NUP98-RARG fusion

    i
    Other names: NUP98, Nucleoporin 98 And 96 Precursor 2, Nuclear Pore Complex Protein Nup98-Nup96 2, Nucleoporin 98kDa, Nucleoporin 96, Nup98-Nup96, Nup98-96, NUP96, Nuclear Pore Complex Protein Nup98, GLFG-Repeat Containing Nucleoporin, NUP98/PHF23 Fusion 2 Protein, Nucleoporin 98kD, Nucleoporin 98, NUP196, ADIR2, ADAR2, RARG, Retinoic Acid Receptor Gamma, NR1B3, RARC, Nuclear Receptor Subfamily 1 Group B Member 3, RAR-Gamma, Retinoic Acid Nuclear Receptor Gamma Variant 1, Retinoic Acid Nuclear Receptor Gamma Variant 2, Retinoic Acid Receptor, Gamma
    Entrez ID:
    4928; 5916
    Related biomarkers:
    Mutation
    Fusion
    Others
    almost2years
    Successful Haploidentical Hematopoietic Stem Cell Transplantation with Azacitidine and Venetoclax Maintenance Therapy for Acute Myeloid Leukemia with NUP98-RARG Gene Fusion. (PubMed, Turk J Haematol)
    No abstract available
    Journal
    |
    NUP98 (Nucleoporin 98 And 96 Precursor 2) • RARG (Retinoic Acid Receptor Gamma)
    |
    NUP98-RARG fusion
    |
    Venclexta (venetoclax) • azacitidine
    over2years
    Identification of a recurrent fusion NUP98-RARG in acute myeloid leukaemia resembling acute promyelocytic leukaemia. (PubMed, Br J Haematol)
    No abstract available
    Journal
    |
    NUP98 (Nucleoporin 98 And 96 Precursor 2) • RARG (Retinoic Acid Receptor Gamma)
    |
    NUP98-RARG fusion
    over2years
    A Novel NUP98/RARG Gene Fusion in Pediatric Acute Myeloid Leukemia Resembling Acute Promyelocytic Leukemia. (PubMed, J Pediatr Hematol Oncol)
    The young male presented with structural and functional abnormalities similar to hypergranular acute promyelocytic leukemia, but was resistant to all transretinoic acids and arsenic trioxide...Disease management may typically require a joint treatment strategy involving chemotherapy, immunotherapy, and support therapy. In this study, we report the clinical manifestations and experimental results of a 10-year-old male and review other cases of RARG gene rearrangement reported in the literature.
    Journal
    |
    NUP98 (Nucleoporin 98 And 96 Precursor 2) • RARG (Retinoic Acid Receptor Gamma)
    |
    NUP98-RARG fusion
    |
    arsenic trioxide