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    BIOMARKER:

    NUP98-NSD1 fusion + FLT3-ITD mutation

    i
    Other names: NSD1, Nuclear Receptor Binding SET Domain Protein 1, ARA267, KMT3B, Histone-Lysine N-Methyltransferase H3 Lysine-36 Specific, Nuclear Receptor-Binding SET Domain-Containing Protein 1, Androgen Receptor-Associated Protein Of 267 KDa, Androgen Receptor Coactivator 267 KDa Protein, NR-Binding SET Domain-Containing Protein, Lysine N-Methyltransferase 3B, H3-K36-HMTase, Histone-Lysine N-Methyltransferase H3 Lysine-36 And H4 Lysine-20 Specific, Truncated Nuclear Receptor Binding SET Domain Protein 1,
    Entrez ID:
    2322; 4928; 64324
    Related biomarkers:
    Expression
    Mutation
    CNA
    Fusion
    Others
    2ms
    Prognostic importance of NUP98-rearrangements in acute myeloid leukemia: A systematic review and meta-analysis. (PubMed, Caspian J Intern Med)
    NUP98 fusions could significantly impact the outcome of patients with AML. The use of these fusions as prognostic indicators in AML seems rational.
    Retrospective data • Review • Journal
    |
    FLT3 (Fms-related tyrosine kinase 3) • NUP98 (Nucleoporin 98 And 96 Precursor 2) • NSD1 (Nuclear Receptor Binding SET Domain Protein 1) • KDM5A (Lysine Demethylase 5A)
    |
    NUP98-NSD1 fusion + FLT3-ITD mutation • NUP98 rearrangement