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    BIOMARKER:

    NUP62 rs9523A>G

    i
    Other names: NUP62, Nucleoporin 62, Nuclear Pore Glycoprotein P62, IBSN, SNDI, P62, 62 KDa Nucleoporin, Nucleoporin 62kDa, Nucleoporin Nup62, DKFZp547L134, FLJ20822, FLJ43869, MGC841, Nucleoporin 62kD
    Entrez ID:
    23636
    over4years
    Nuclear Pore Glycoprotein 62 Genetic Variant rs9523 is Associated with Clinical Outcomes of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Lung Adenocarcinoma Patients. (PubMed, Pharmgenomics Pers Med)
    In addition, a significantly decreased luciferase activity was noted in NUP62 rs9523 G allele compared to A allele. Genetic variants in miRNA binding sites, especially NUP62 rs9523A>G, may be useful in predicting the clinical outcomes of EGFR-mutant lung adenocarcinoma patients treated with EGFR-TKIs.
    Clinical • Clinical data • Journal
    |
    EGFR (Epidermal growth factor receptor) • NUP62 (Nucleoporin 62)
    |
    EGFR mutation • NUP62 rs9523A>G