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    BIOMARKER:

    NFKB1 overexpression

    i
    Other names: NFKB1, KBF1, NF-kappaB, NF-kB1, NFkappaB, NFKB-p50, p105, p50, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
    Entrez ID:
    4790
    Related biomarkers:
    Expression
    7ms
    Prostate cancer invasion is promoted by the miR-96-5p-induced NDRG1 deficiency through NF-κB regulation. (PubMed, Klin Onkol)
    MiR-96-5p promotes the migration and invasion of PCa by targeting NDRG1 and regulating the NF-kB pathway.
    Journal
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    MYCN (MYCN Proto-Oncogene BHLH Transcription Factor) • MIR96 (MicroRNA 96) • NDRG1 (N-Myc Downstream Regulated 1) • NFKBIA (NFKB Inhibitor Alpha 2)
    |
    NFKB1 overexpression • NDRG1 overexpression
    1year
    Synthesis Folate-linked Chitosan-coated Quetiapine/BSA Nano-Carriers as the Efficient Targeted Anti-Cancer Drug Delivery System. (PubMed, Mol Biotechnol)
    The efficient selective cytotoxic impact of FCQB-NCs can be due to the novel stepwise release mechanism of the FCQB-NCs based on the two-phase entrapment of QTP by BSA and chitosan molecules. Therefore, FCQB-NCs have the potential to be used as an efficient selective anti-breast cancer.
    Journal
    |
    MMP2 (Matrix metallopeptidase 2) • MMP9 (Matrix metallopeptidase 9)
    |
    NFKB1 overexpression
    2years
    Genomic Aberrations Generate Fusion Gene FOXK2::TP63 and Activate NFKB1 in Cutaneous T-Cell Lymphoma. (PubMed, Biomedicines)
    Finally, treatment of HH with NFkB inhibitor demonstrated a role for NFkB in supporting proliferation, while usage of inhibitor DAPT showed significant survival effects via the NOTCH pathway. Collectively, our data suggest that NFkB and/or NOTCH inhibitors may represent reasonable treatment options for subsets of CTCL patients.
    Journal
    |
    MIR155 (MicroRNA 155) • IRF4 (Interferon regulatory factor 4) • IKZF2 (IKAROS family zinc finger 2) • TP63 (Tumor protein 63) • CAMK2D (Calcium/Calmodulin Dependent Protein Kinase II Delta) • NFKB2 (Nuclear Factor Kappa B Subunit 2)
    |
    NFKB1 overexpression • NFKB1 expression
    over2years
    Identify Bcl3 as a novel biomarker shared between severe asthma and lung cancer using next-generation RNA sequencing from archival FFPE tissue biopsies (ERS 2022)
    Our findings indicate a Bcl3 a novel putative biomarker in pathogeneses of both severe asthma and lung cancer.
    CD44 (CD44 Molecule) • STAT1 (Signal Transducer And Activator Of Transcription 1) • BCL3 (BCL3 Transcription Coactivator)
    |
    NFKB1 overexpression • BCL3 overexpression
    almost4years
    The transcription factor NF-kB1 regulates miR-195 expression in prostate cancer (PubMed, Zhonghua Nan Ke Xue)
    NF-kB1 regulates the expression of miR-195 in prostate cancer.
    Journal
    |
    NFKB1 (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) • MIR195 (MicroRNA 195)
    |
    NFKB1 overexpression • NFKB1 expression