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    BIOMARKER:

    MUC20 underexpression

    i
    Other names: MUC20, Mucin 20 Cell Surface Associated, KIAA1359, FLJ14408, Mucin-20, MUC-20, Transmembrane Mucin MUC20S
    Entrez ID:
    200958
    over2years
    MUC20 as a novel prognostic biomarker in ccRCC correlating with tumor immune microenvironment modulation. (PubMed, Am J Cancer Res)
    Additionally, the patients with low MUC20 expression had better response to immune checkpoint blockades (ICBs) and 17 potential anticancer drugs were screened regarding calculating IC value. Thus, MUC20 may contain a value of prognosis assessment for ccRCC patients and indicate the immune modulation status of TME, which provided a novel insight for comprehensive immunotherapy.
    Journal • IO biomarker
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    CD8 (cluster of differentiation 8) • CD4 (CD4 Molecule) • MUC20 (Mucin 20 Cell Surface Associated)
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    MUC20 underexpression