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DRUG CLASS:

MUC16-targeted antibody-drug conjugate

Related drugs:
3years
An open-label phase I dose-escalation study of the safety and pharmacokinetics of DMUC4064A in patients with platinum-resistant ovarian cancer. (PubMed, Gynecol Oncol)
In this Phase I study, DMUC4064A demonstrated a tolerable safety profile along with encouraging efficacy in the indication of platinum-resistant OC.
Clinical • P1 data • PK/PD data • Journal
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MUC16 (Mucin 16, Cell Surface Associated) • MUC4 (Mucin 4, Cell Surface Associated)
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MUC1 overexpression • MUC16 expression
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RG7882