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    BIOMARKER:

    MSH6 F1088fs

    i
    Other names: MSH6, GTBP, MutS homolog 6
    Entrez ID:
    2956
    Related biomarkers:
    Expression
    Mutation
    CNA
    Others
    over2years
    Difference analysis of somatic mutations between deficient mismatch repair and proficient mismatch repair gene related with colorectal cancer (PubMed, Zhonghua Zhong Liu Za Zhi)
    The BRAF V600E mutation is closely related to dMMR. KRAS G13D, BLM N515fs and PTCH1 R1308fs mutation sites are also associated with the expression of MMR proteins.
    Journal • Mismatch repair • BRCA Biomarker
    |
    EGFR (Epidermal growth factor receptor) • HER-2 (Human epidermal growth factor receptor 2) • KRAS (KRAS proto-oncogene GTPase) • BRAF (B-raf proto-oncogene) • TP53 (Tumor protein P53) • PIK3CA (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha) • BRCA1 (Breast cancer 1, early onset) • BRCA2 (Breast cancer 2, early onset) • PDGFRA (Platelet Derived Growth Factor Receptor Alpha) • MLH1 (MutL homolog 1) • PTCH1 (Patched 1) • MSH6 (MutS homolog 6) • MSH2 (MutS Homolog 2) • PMS2 (PMS1 protein homolog 2)
    |
    BRAF V600E • KRAS mutation • MSI-H/dMMR • BRAF V600 • HER-2 mutation • KRAS G13D • PTCH1 mutation • KRAS G13 • MSH2 mutation • PMS2 mutation • BLM mutation • MSH6 F1088fs • MSH6 expression