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GENE:

MLN (Motilin)

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Other names: MLN, Motilin, Prepromotilin, Promotilin
Associations
Trials
5ms
Impact of Nutritional Support Under Comprehensive Nursing on Gastrointestinal Function in Patients With Gastroparesis Syndrome Following Radical Gastrectomy for Gastric Cancer. (PubMed, Ann Ital Chir)
Nutritional support intervention delivered through comprehensive nursing for patients with gastroparesis syndrome after radical gastrectomy for gastric cancer enhances gastric function, modulates gastrointestinal hormone levels, alleviates gastroparesis symptoms, and improves nursing satisfaction.
Journal
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GAST (Gastrin 2) • MLN (Motilin)
12ms
Association of chemotherapy-induced nausea and vomiting or anorexia with plasma levels of five gastrointestinal peptides in patients receiving chemotherapy. (PubMed, J Pharm Health Care Sci)
CINV is associated with excessive secretion of motilin and anorexia is related to sustained elevation of leptin, suggesting the potential of these peptides as quantitative indicators of CINV and anorexia.
Journal
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LEP (Leptin) • MLN (Motilin)
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cisplatin
1year
Changtong paste improves gastrointestinal function of patients after colorectal cancer surgery. (PubMed, Am J Transl Res)
Changtong Paste therapy can effectively regulate hemorheology, improve gastrointestinal hormone levels, promote gastrointestinal and immune function recovery, alleviate cancer-related fatigue, enhance quality of life, and shorten hospital stays after colorectal cancer surgery.
Journal • Surgery
|
MLN (Motilin)
over1year
Relationship between postoperative rehabilitation style, gastrointestinal function, and inflammatory factor levels in children with intussusception. (PubMed, World J Gastrointest Surg)
We found a positive correlation between gastrointestinal function and postoperative rehabilitation training, and a negative correlation between inflammatory factor levels and rehabilitation training in children with intussusception.
Journal
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IL6 (Interleukin 6) • TNFA (Tumor Necrosis Factor-Alpha) • IL10 (Interleukin 10) • GAST (Gastrin 2) • IL4 (Interleukin 4) • CRP (C-reactive protein) • MLN (Motilin)
over1year
A comparative study of acupuncture combined with rehabilitation gymnastics on postoperative anal function of lower rectal cancer. (PubMed, World J Clin Cases)
Acupuncture combined with rehabilitation gymnastics can promote the recovery of anal function and reduce the inflammatory response in patients with lower rectal cancer after surgery.
Clinical • Journal
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IL6 (Interleukin 6) • IL10 (Interleukin 10) • IL4 (Interleukin 4) • MLN (Motilin)
over1year
Evaluating the clinical application and effect of acupuncture therapy in anal function rehabilitation after low-tension rectal cancer surgery. (PubMed, World J Clin Cases)
Acupuncture therapy has a positive effect on the rehabilitation of anal function after low-tension rectal cancer surgery; it can effectively help to improve the serum indices of patients, avoid the occurrence of anal incontinence, and reduce the incidence of complications. Popularizing and applying it will be valuable.
Journal • Surgery
|
MLN (Motilin)
|
loperamide
almost2years
Treatment Effects of Bifidobacterium Quadruple Viable Tablets Combined With Quadruple Therapy on Helicobacter Pylori-Infected Peptic Ulcer in Children. (PubMed, Clin Pediatr (Phila))
After treatment, the children in the observation group possessed lower serum interleukin-6, tumor necrosis factor α, procalcitonin, C-reactive protein, gastrin, and motilin levels, and higher ulcer healing rate, Hp clearance rate, somatostatin levels and bifidobacterium and lactobacillus versus those in the control group. Bifidobacterium quadruple viable tablets combined with quadruple therapy has good efficacy in Hp-associated peptic ulcer disease.
Journal
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IL6 (Interleukin 6) • TNFA (Tumor Necrosis Factor-Alpha) • GAST (Gastrin 2) • CRP (C-reactive protein) • MLN (Motilin)
2years
Surgical effect and gastrointestinal functional recovery of laparoscopic-guided total mesorectal excision in patients with rectal cancer. (PubMed, J Minim Access Surg)
LGTME improves the surgical effects of rectal cancer patients, promotes the recovery of gastrointestinal function and has a small effect on anal function indicators, thereby reducing hospital stay.
Journal
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FGF (Fibroblast Growth Factor) • GAST (Gastrin 2) • MLN (Motilin)
2years
The influence of herbal medicine on serum motilin and its effect on human and animal model: a systematic review. (PubMed, Front Pharmacol)
Further studies with more solid evidence are needed to confirm the efficacy and mechanisms of action of herbal medicines. Systematic Review Registration: https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=443244, identifier CRD42023443244.
Preclinical • Review
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GAST (Gastrin 2) • MLN (Motilin)
over2years
Effect of melatonin in patients with low anterior resection syndrome (MELLARS): a study protocol for a randomised, placebo-controlled, crossover trial. (PubMed, BMJ Open)
The results of the study will be submitted to peer-reviewed journals for publication and presented at congresses. EudraCT Registry (2020-004442-11) and ClinicalTrial.gov Registry (NCT05042700).
Journal
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MLN (Motilin)
over3years
Journal
|
GAST (Gastrin 2) • MLN (Motilin)
|
loperamide
over3years
Analysis of gastrointestinal function and prognostic value of tumor markers in patients with laparoscopic radical resection of colorectal cancer. (PubMed, Am J Transl Res)
LRRCC is well-tolerated by patients with CC and contributes to favorable outcomes. Besides, CEA and CA19-9, the two TMs, may be candidate prognostic markers for patients undergoing LRRCC.
Journal
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CEACAM5 (CEA Cell Adhesion Molecule 5) • GAST (Gastrin 2) • CA 19-9 (Cancer antigen 19-9) • MLN (Motilin)