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    DRUG:

    miRNA-520f

    i
    Other names: miRNA-520f, microRNA therapeutic
    Associations

    News

    Trials
    Company:
    InteRNA Tech
    Drug class:
    ADAM9 inhibitor, TGF-β2 inhibitor
    Related drugs:
    Associations

    News

    Trials
    4years
    MicroRNA-520f-3p inhibits proliferation of gastric cancer cells via targeting SOX9 and thereby inactivating Wnt signaling. (PubMed, Sci Rep)
    Together our findings thus suggest that miR-520f-3p can act to suppress GC progression, at least in part via suppressing SOX9 expression and thus disrupting Wnt/β-catenin signaling. Our results thus highlight potential novel therapeutic targets in GC worthy of future investigation.
    Journal
    |
    SOX9 (SRY-Box Transcription Factor 9)
    |
    SOX9 expression
    |
    miRNA-520f