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DRUG:

miRNA-520f

i
Other names: miRNA-520f, microRNA therapeutic
Associations
Trials
Company:
InteRNA Tech
Drug class:
ADAM9 inhibitor, TGF-β2 inhibitor
Associations
Trials
almost4years
MicroRNA-520f-3p inhibits proliferation of gastric cancer cells via targeting SOX9 and thereby inactivating Wnt signaling. (PubMed, Sci Rep)
Together our findings thus suggest that miR-520f-3p can act to suppress GC progression, at least in part via suppressing SOX9 expression and thus disrupting Wnt/β-catenin signaling. Our results thus highlight potential novel therapeutic targets in GC worthy of future investigation.
Journal
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SOX9 (SRY-Box Transcription Factor 9)
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SOX9 expression
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miRNA-520f