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    GENE:

    MIR887 (MicroRNA 887)

    i
    Other names: MIR887, MicroRNA 887, Hsa-MiR-887-3p, Hsa-Mir-887, MIRN887, Hsa-Mir-887_pre, Hsa-MiR-887-5p, MIMAT0004951, MIMAT0026720, MI0005562
    Associations

    News

    Trials
    9ms
    A 3-miRNA signature for noninvasive breast cancer detection. (PubMed, Semin Oncol)
    Similarly, significant prognostic clinical characteristics were observed for these miRNAs. Overall, we have identified and validated a novel and proficient signature biomarker in serum of BC patients consisting of 3 miRNAs.
    Journal
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    MIR887 (MicroRNA 887) • MIRLET7E (MicroRNA Let-7e)
    over3years
    miR-887-3p Inhibits the Progression of Colorectal Cancer via Downregulating DNMT1 Expression and Regulating P53 Expression. (PubMed, Comput Intell Neurosci)
    It inhibited CRC cell proliferation, invasion, and EMT, and promoted cell apoptosis through targeting and downregulating DNMT1 and promoting P53 expression. Therefore, miR-887-3p may be a good biomarker and therapeutic target for CRC treatment.
    Journal
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    TP53 (Tumor protein P53) • DNMT1 (DNA methyltransferase 1) • MIR887 (MicroRNA 887)
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    TP53 expression • DNMT1 expression • DNMT1 overexpression