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    GENE:

    MIR6870 (MicroRNA 6870)

    i
    Other names: MIR6870, MicroRNA 6870, Hsa-Mir-6870, MicroRNA Mir-6870, MIMAT0027641, MIMAT0027640, MI0022717
    Associations

    News

    Trials
    over1year
    Dysregulation of plasma circulating microRNAs in all-cause and cause-specific cancers: the Rotterdam Study. (PubMed, Biomark Res)
    While no significant miRNA association was found for other four studied cancers, two miRNAs (miR-3157-5p and miR-3912-5p) showed nominal association with incident of three different cancer types. Overall, this study indicates that plasma levels of several miRNAs are dysregulated in hematologic tumors, highlighting their potential as biomarkers for early diagnosis as well as being involved in the pathogenesis of blood cancers.
    Journal
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    MIR1915 (MicroRNA 1915) • MIR4644 (MicroRNA 4644) • MIR6870 (MicroRNA 6870)
    over2years
    MicroRNA networks linked with BRCA1/2, PTEN, and common genes for Alzheimer's disease and breast cancer share highly enriched pathways that may unravel targets for the AD/BC comorbidity treatment. (PubMed, Comput Biol Chem)
    Those 49 miRNAs regulate the expression of 122 genes in AD and 93 genes in BC, from which 26 genes are common genes for AD and BC involved in neuron differentiation and genesis, cell differentiation and migration, regulation of cell cycle, and cancer development. Additionally, the highly enriched pathway was associated with diabetic complications, pointing out possible interplay among molecules underlying BC, AD, and diabetes pathology.
    Journal • BRCA Biomarker
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    BRCA1 (Breast cancer 1, early onset) • BRCA2 (Breast cancer 2, early onset) • PTEN (Phosphatase and tensin homolog) • MIR17HG (MiR-17-92a-1 Cluster Host Gene) • MIR17 (MicroRNA 17) • MIR124-3 (MicroRNA 124-3) • MIR6127 (MicroRNA 6127) • MIR6785 (MicroRNA 6785) • MIR6870 (MicroRNA 6870) • MIR8485 (MicroRNA 8485)