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    GENE:

    MIR644A (MicroRNA 644a)

    i
    Other names: MIR644A, MicroRNA 644a, Hsa-Mir-644, MicroRNA 644, MIRN644, MIR644, Hsa-Mir-644a, MIMAT0003314, Hsa-MiR-644a, MI0003659, RF01037
    Associations

    News

    Trials
    1year
    miR-644a is a tumor cell-intrinsic mediator of sex bias in glioblastoma. (PubMed, Neurooncol Adv)
    Among patient-derived models, miR-644a was expressed a median of 4.8-fold higher in females compared to males. Our findings implicate miR-644a as a candidate tumor cell-intrinsic regulator of sex-biased gene expression in GBM.
    Journal • Tumor cell
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    MIR644A (MicroRNA 644a)
    3years
    LncRNA BCAR4 promotes migration, invasion, and chemo-resistance by inhibiting miR-644a in breast cancer. (PubMed, J Exp Clin Cancer Res)
    Our findings provide insights into the oncogenic role of BCAR4 and implicate BCAR4 as a potential diagnostic biomarker and a promising therapeutic agent to suppress metastasis and inhibit chemo-resistance of breast cancer.
    Journal
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    ABCB1 (ATP Binding Cassette Subfamily B Member 1) • CCR7 (Chemokine (C-C motif) receptor 7) • BCAR4 (Breast Cancer Anti-Estrogen Resistance 4) • MIR644A (MicroRNA 644a)
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    ABCB1 expression
    3years
    Hsa_circ_0007380 silencing restrains the growth and enhances radiosensitivity in esophagus cancer by miR-644a/Spindlin 1 axis. (PubMed, Anticancer Drugs)
    Besides that, inhibition of miR-644a abolished the promoting action of hsa_circ_0007380 knockdown on esophagus cancer apoptosis and radiosensitivity. Hsa_circ_0007380 silencing impedes cell growth and reinforces radiosensitivity in esophagus cancer by miR-644a/SPIN1 axis, suggesting a promising therapeutic target for esophagus cancer combined treatment.
    Journal
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    MIR644A (MicroRNA 644a)