MIR640 (MicroRNA 640)

News alerts, weekly reports and conference planners

almost2years

Circulating microRNAs in association with pancreatic cancer risk within 5 years. (PubMed, Int J Cancer)

The miRNA targets were enriched in pancreatic carcinogenesis/progression-related pathways. Our study suggests that circulating miRNAs may identify individuals at high risk for pancreatic cancer ≤5 years prior to diagnosis, indicating its potential utility in cancer screening and surveillance.

almost 2 years ago

Journal

MIR199A1 (MicroRNA 199a-1) • MIR199B (MicroRNA 199b) • MIR199A (MicroRNA 199a) • MIR1299 (MicroRNA 1299) • MIR191 (MicroRNA 191) • MIR22 (MicroRNA 22) • MIR640 (MicroRNA 640)

over2years

Paclitaxel inhibits hepatocellular carcinoma tumorigenesis by regulating the circ_0005785/miR-640/GSK3β. (PubMed, Cell Biol Int)

Mechanistically, circ_0005785 acted as a sponge of miR-640 to regulate GSK3β expression. PTX restrained HCC tumorigenesis partly via regulating the circ_0005785/miR-640/GSK3β axis, hinting at a promising therapeutic target for the HCC treatment.

over 2 years ago

Journal • IO biomarker

BCL2 (B-cell CLL/lymphoma 2) • PCNA (Proliferating cell nuclear antigen) • GSK3B (Glycogen Synthase Kinase 3 Beta) • MIR640 (MicroRNA 640)

paclitaxel

over3years

Hsa_circ_0097271 Knockdown Attenuates Osteosarcoma Progression via Regulating miR-640/MCAM Pathway. (PubMed, Dis Markers)

MCAM knockdown repressed OS cell growth and migration, while additional miR-640 depletion partially abolished the anticancer effects of MCAM knockdown in OS cells. Circ_0097271 is an oncogenic driver and contributes to OS development via targeting the miR-640/MCAM pathway, which provides a potential opinion for OS treatment.

over 3 years ago

Journal

MIR640 (MicroRNA 640)

MCAM expression