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GENE:

MIR6127 (MicroRNA 6127)

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Other names: MIR6127, MicroRNA 6127, Hsa-Mir-6127, MicroRNA Mir-6127, MIMAT0024610, MI0021271
Associations
Trials
over2years
MicroRNA networks linked with BRCA1/2, PTEN, and common genes for Alzheimer's disease and breast cancer share highly enriched pathways that may unravel targets for the AD/BC comorbidity treatment. (PubMed, Comput Biol Chem)
Those 49 miRNAs regulate the expression of 122 genes in AD and 93 genes in BC, from which 26 genes are common genes for AD and BC involved in neuron differentiation and genesis, cell differentiation and migration, regulation of cell cycle, and cancer development. Additionally, the highly enriched pathway was associated with diabetic complications, pointing out possible interplay among molecules underlying BC, AD, and diabetes pathology.
Journal • BRCA Biomarker
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BRCA1 (Breast cancer 1, early onset) • BRCA2 (Breast cancer 2, early onset) • PTEN (Phosphatase and tensin homolog) • MIR17HG (MiR-17-92a-1 Cluster Host Gene) • MIR17 (MicroRNA 17) • MIR124-3 (MicroRNA 124-3) • MIR6127 (MicroRNA 6127) • MIR6785 (MicroRNA 6785) • MIR6870 (MicroRNA 6870) • MIR8485 (MicroRNA 8485)