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    GENE:

    MIR4644 (MicroRNA 4644)

    i
    Other names: MIR4644, MicroRNA 4644, Hsa-Mir-4644, MIMAT0019704, Hsa-MiR-4644, MI0017271
    Associations

    News

    Trials
    4ms
    Screening and regulatory mechanisms of biomarkers related to neddylation in laryngeal squamous cell carcinoma. (PubMed, Front Mol Biosci)
    WSB2 and COMMD2 jointly predicted that hsa-miR-185-5p, hsa-miR-4644 and hsa-miR-4306 were the common microRNAs (miRNAs) and regulatory networks. This study successfully established a neddylation-associated prognostic risk model for LSCC and revealed that COMMD2, WSB2, and CUL9 could act as new therapeutic targets, which might provide valuable information for the research and treatment of LSCC.
    Journal
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    WSB2 (WD Repeat And SOCS Box Containing 2) • miR-185 (MicroRNA 185) • MIR4306 (MicroRNA 4306) • CUL9 (Cullin 9) • MIR4644 (MicroRNA 4644)
    over1year
    Dysregulation of plasma circulating microRNAs in all-cause and cause-specific cancers: the Rotterdam Study. (PubMed, Biomark Res)
    While no significant miRNA association was found for other four studied cancers, two miRNAs (miR-3157-5p and miR-3912-5p) showed nominal association with incident of three different cancer types. Overall, this study indicates that plasma levels of several miRNAs are dysregulated in hematologic tumors, highlighting their potential as biomarkers for early diagnosis as well as being involved in the pathogenesis of blood cancers.
    Journal
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    MIR1915 (MicroRNA 1915) • MIR4644 (MicroRNA 4644) • MIR6870 (MicroRNA 6870)
    2years
    Identification of AP002498.1 and LINC01871 as prognostic biomarkers and therapeutic targets for distant metastasis of colorectal adenocarcinoma. (PubMed, Cancer Med)
    The DElncRNA AP002498.1 and the LINC01871/miR-4644 and miR-185-5p/GNLY axes were identified as being closely associated with distant metastasis and could represent independent prognostic biomarkers or therapeutic targets in colorectal adenocarcinoma.
    Journal • IO biomarker
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    CXCL10 (Chemokine (C-X-C motif) ligand 10) • IDO1 (Indoleamine 2,3-dioxygenase 1) • CXCL9 (Chemokine (C-X-C motif) ligand 9) • MUC5B (Mucin 5B, Oligomeric Mucus/Gel-Forming) • NOS2 (Nitric Oxide Synthase 2) • miR-185 (MicroRNA 185) • GBP4 (Guanylate Binding Protein 4) • LINC01871 (Long Intergenic Non-Protein Coding RNA 1871) • SERPINA1 (Serpin Family A Member 1) • MIR4644 (MicroRNA 4644)
    over2years
    Tumor-derived exosome ElNF1-AS1 affects the progression of gastric cancer by promoting M2 polarization of macrophages. (PubMed, Environ Toxicol)
    The study suggests that ELFN1-AS1 could be a promising biomarker for the diagnosis and treatment of GC.
    Journal
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    HIF1A (Hypoxia inducible factor 1, alpha subunit) • PKM (Pyruvate Kinase M1/2) • MIR4644 (MicroRNA 4644)
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    HIF1A expression