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    GENE:

    MIR429 (MicroRNA 429)

    i
    Other names: MIR429 ,MicroRNA 429, Hsa-MiR-429, Mir-429, MIRN429, MIR429
    20d
    ETS Variant Transcription Factor 6 Promotes Glucose Metabolism Reprogramming in HCC. (PubMed, J Cell Mol Med)
    Mechanistically, ETV6 binds to the miR-429 promoter, mediating glucose metabolic reprogramming in HCC cells by targeting CRKL via the PI3K/AKT pathway. Taken together, these findings reveal that the ETV6-miR-429-CRKL regulatory circuitry plays a crucial role in glucose metabolic reprogramming in HCC, offering novel insight and a potential target for cancer therapy.
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    ETV6 (ETS Variant Transcription Factor 6) • CRKL (CRK Like Proto-Oncogene, Adaptor Protein) • MIR429 (MicroRNA 429) • TFAM (Transcription Factor A, Mitochondrial)
    24d
    [Retracted] MicroRNA-429 inhibits gastric cancer migration and invasion through the downregulation of specificity protein 1. (PubMed, Oncol Lett)
    [This retracts the article DOI: 10.3892/ol.2017.5869.].
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    MIR429 (MicroRNA 429)
    28d
    Tissue expression of miR-504-5p and miR-429 as diagnostic biomarkers for endometrial cancer and endometrial intraepithelial neoplasia: a pilot study. (PubMed, J Liq Biopsy)
    This two-miRNA panel could complement histopathology in distinguishing precursor lesions from carcinoma, addressing a key diagnostic challenge. Larger studies, including minimally invasive liquid biopsy approaches, are warranted to validate their clinical utility.
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    MIR429 (MicroRNA 429) • MIR504 (MicroRNA 504)
    2ms
    miRquad: first-in-class dPCR multiplex TaqMan™ Advanced clinical research assay for microRNA detection in head and neck cancer. (PubMed, J Exp Clin Cancer Res)
    The assay overcomes common challenges associated with multiple miRNAs detection, particularly in liquid biopsy samples (e.g., multiple pipetting issues, increased consumption of sample for multiple assessment, extended TAT for complete profiling) and provides robust and accurate detection, demonstrating potential for real-time patient monitoring and prognostication in HNC.
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    MIR21 (MicroRNA 21) • MIR429 (MicroRNA 429) • MIR96 (MicroRNA 96)
    3ms
    Stage- and smoking-associated microRNA expression in lung adenocarcinoma. (PubMed, Transl Lung Cancer Res)
    Among the miRNA alterations associated with stage I adenocarcinoma in nonsmokers, we found alterations in all 5 miR-200 family members (miR-200b, miR-200a, miR-141, miR-429, and miR-200c). Our identification of miRNA alterations associated with early-stage lung adenocarcinoma in nonsmokers, especially alterations in the miR-200 family, suggests that these miRNAs may play a unique role in the early stages of lung carcinogenesis and progression in nonsmokers and that they may be useful as markers for the early detection of lung cancer.
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    MIR200B (MicroRNA 200b) • MIR200C (MicroRNA 200c) • MIR429 (MicroRNA 429) • MIR200A (MicroRNA 200a) • MIR141 (MicroRNA 141) • MIR200 (MicroRNA 200)
    3ms
    KY216-tubulin complex captures VASH2 to inhibit NSCLC metastasis. (PubMed, Nat Commun)
    Additionally, KY216 elevates the levels of miR-429 to target the 3'-untranslated region (3' UTR) of VASH2 and ZEB1 transcripts and inhibits EMT, at least partially, via the miR-429/VASH2/ZEB1 axis to block NSCLC metastasis. Overall, our investigation offers valuable insights into the roles of MTAs and VASH2 in NSCLC metastasis.
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    MIR429 (MicroRNA 429) • VASH2 (Vasohibin 2) • ZEB1 (Zinc Finger E-box Binding Homeobox 1)
    3ms
    Circulating MiRNAs in thyroid cancer: prognostic promise of miR-155 and limitations of miR-429. (PubMed, Mol Biol Rep)
    miR-155 appears to be a promising minimally invasive biomarker for thyroid malignancy, while miR-429 cannot reliably distinguish malignant from non-malignant lesions; further studies are needed to validate these findings.
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    MIR155 (MicroRNA 155) • MIR429 (MicroRNA 429)
    3ms
    Evaluation of genes and molecular pathways involved in ferroptosis in breast cancer: A systems biology and bioinformatics approach. (PubMed, Biochem Biophys Rep)
    Our findings highlight that hub genes like EZH2 and PTEN are potential biomarkers and therapeutic targets for modulating ferroptosis in breast cancer. These results provide a strong foundation for future experimental validation to translate computational insights into clinical applications.
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    PTEN (Phosphatase and tensin homolog) • MIR429 (MicroRNA 429)
    3ms
    MiRNome alterations drive the malignant transformation of endometriosis into endometriosis-correlated ovarian cancer. (PubMed, Sci Rep)
    Evaluation of miRNAs commonly deregulated between the three groups showed 14 shared upregulated miRNAs (miR-429, miR-425-5p, miR-200c-3p, miR-200c-5p, miR-200b-3p, miR-200a-3p, miR-183-5p, miR-182-5p, miR-141-5p, miR-141-3p, miR-96-5p, miR-93-5p, miR-10a-5p, miR-10a-3p) with a progressive increase in expression levels, from ovarian EMS to TL and ultimately to ECOC. The identified miRNA expression profiles associated with the progression from ovarian EMS, TL and ECOC provide valuable insights into the molecular progression from benign to malignant lesions and could represent potential biomarkers for the early detection of ECOC.
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    MIR200B (MicroRNA 200b) • MIR200C (MicroRNA 200c) • MIR429 (MicroRNA 429) • MIR200A (MicroRNA 200a) • MIR96 (MicroRNA 96) • MIR141 (MicroRNA 141) • MIR182 (MicroRNA 182) • MIR425 (MicroRNA 425) • MIR183 (MicroRNA 183) • MIR93 (MicroRNA 93)
    5ms
    Diagnostic and prognostic potential of microRNA profiles in endometrioid endometrial cancer. (PubMed, Sci Rep)
    We showed that miRNAs have good diagnostic sensitivity for identifying EEC and EC grading. In addition, miRNA improved the ability to discriminate between ECs of different grades.
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    KRAS (KRAS proto-oncogene GTPase) • PTEN (Phosphatase and tensin homolog) • CTNNB1 (Catenin (cadherin-associated protein), beta 1) • MIR200B (MicroRNA 200b) • MIR21 (MicroRNA 21) • MIR200C (MicroRNA 200c) • MIR429 (MicroRNA 429) • MIR30B (MicroRNA 30b) • MIR324 (MicroRNA 324) • MIR543 (MicroRNA 543) • MIR96 (MicroRNA 96) • Let-7c (MicroRNA Let-7c) • MIR126 (MicroRNA 126) • MIR141 (MicroRNA 141) • MIR182 (MicroRNA 182) • MIR18A (MicroRNA 18a) • MIR129 (MicroRNA 129) • MIR129-2 (MicroRNA 129-2) • MIR130A (MicroRNA 130a) • MIR181B1 (MicroRNA 181b-1) • MIR183 (MicroRNA 183) • MIR203A (MicroRNA 203a) • MIR205 (MicroRNA 205) • MIR217 (MicroRNA 217) • MIR30C • MIRLET7E (MicroRNA Let-7e)
    5ms
    The miR-200 family in the context of obesity and type 2 diabetes. (PubMed, Diabetes Res Clin Pract)
    Functional enrichment analysis revealed pathways associated with insulin signaling, inflammation, and immune response. These results highlight the potential of miR-200 family members as biomarkers and therapeutic targets in metabolic disease.
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    MIR200B (MicroRNA 200b) • MIR200C (MicroRNA 200c) • MIR429 (MicroRNA 429) • MIR141 (MicroRNA 141) • MIR200 (MicroRNA 200)
    6ms
    In Situ MicroRNA Profiling of Single Tumor Extracellular Vesicles for Precise Prostate Cancer Diagnosis. (PubMed, Anal Chem)
    The miR-nSTEV assay demonstrated superior diagnostic performance, achieving 100% accuracy in distinguishing PCa patients from healthy donors (HD), outperforming conventional RT-qPCR while simplifying the workflow. Overall, miR-nSTEV offers a robust, sensitive, and noninvasive tool for real-time TEV miRNA analysis, paving the way for early detection and precision diagnostics in PCa patients.
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    EPCAM (Epithelial cell adhesion molecule) • MIR429 (MicroRNA 429) • MIR18A (MicroRNA 18a) • MIR183 (MicroRNA 183)