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    GENE:

    MIR3178 (MicroRNA 3178)

    i
    Other names: MIR3178, MicroRNA 3178, Hsa-Mir-3178, MIMAT0015055, Hsa-MiR-3178, MI0014212, Mir-3178
    Associations

    News

    Trials
    over1year
    The Association Between Anti-Neoplastic Effects of Curcumin and Urogenital Cancers: A Systematic Review. (PubMed, Biomed Res Int)
    Curcumin exerts its anticancer effects on urogenital neoplasms by upregulating tumor suppressor microRNAs (miR-143, miR-145, miR-Let-7, miR-101, miR-3127, miR-3178, miR-1275, miR-3198, miR-1908, miR-770, miR-1247, miR-411, miR-34a, miR-383, miR-708, miR-483, miR-199a, miR-335, miR-503, miR-10b, miR-551a, miR-9, miR-203, miR-7110, miR-29b, and miR-126) and downregulating oncogenic microRNAs (miR-21, miR-210, miR-382, miR-654, miR-494, miR-193b, miR-671, miR-222, miR-23b, miR-664, miR-183, miR-214, miR-320a, miR-23a, miR-30a, miR-320d, miR-1285, miR-32, miR-181a, miR-205, miR-216a, miR-1246, and miR-106b). Cell proliferation is inhibited, and cell apoptosis is induced by curcumin in different urogenital cancers through suppressing oncogenic microRNAs or provoking tumor suppressor microRNAs.
    Review • Journal
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    MIR21 (MicroRNA 21) • MIR34A (MicroRNA 34a-5p) • MIR193B (MicroRNA 193b) • MIR1246 (MicroRNA 1246) • MIR126 (MicroRNA 126) • MIR143 (MicroRNA 143) • MIR199A (MicroRNA 199a) • MIR210 (MicroRNA 210) • MIR216A (MicroRNA 216a) • MIR23A (MicroRNA 23a) • MIR23b (MicroRNA 23b) • MIR320A (MicroRNA 320a) • MIR335 (MicroRNA 335) • MIR494 (MicroRNA 494) • MIR503 (MicroRNA 503) • MIR664A (MicroRNA 664a) • MIR106B (MicroRNA 106b) • MIR10B (MicroRNA 10b) • MIR1247 (MicroRNA 1247) • MIR127 (MicroRNA 127) • MIR145 (MicroRNA 145) • MIR181A1 (MicroRNA 181a-1) • MIR183 (MicroRNA 183) • MIR203A (MicroRNA 203a) • MIR205 (MicroRNA 205) • MIR214 (MicroRNA 214) • MIR222 (MicroRNA 222) • MIR30A (MicroRNA 30a) • MIR3178 (MicroRNA 3178) • MIR383 (MicroRNA 383) • MIR483 (MicroRNA 483) • MIR671 (MicroRNA 671) • MIR708 (MicroRNA 708)
    over2years
    The influence of selected microRNAs on the expression profile of genes and proteins related to the tumor necrosis factor-alpha signaling pathways in endometrioid endometrial cancer. (PubMed, J Cancer Res Clin Oncol)
    TNF-α signaling, especially the TNF-α/NF-κB axis, is disrupted in endometrial cancer and worsens with disease progression. The observed changes may be the result of miRNAs' activity in the initial stage of endometrial cancer and its gradual loss in later grades.
    Journal
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    TNFA (Tumor Necrosis Factor-Alpha) • CAV1 (Caveolin 1) • TNFRSF1A (TNF Receptor Superfamily Member 1A) • TGFB1 (Transforming Growth Factor Beta 1) • MIR572 (MicroRNA 572) • MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7) • MIR1207 (MicroRNA 1207) • MIR3178 (MicroRNA 3178)
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    CAV1 overexpression