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    GENE:

    MIR1-1 (MicroRNA 1-1)

    i
    Other names: MIR1-1, MicroRNA 1-1, Hsa-MiR-1-3p, Hsa-Mir-1-1, MIRN1-1, Hsa-Mir-1-P3_pre, MIMAT0031892, MIMAT0000416, Hsa-MiR-1-5p, MI0000651, MiRNA1-1, Mir-1-1, RF00103
    Associations

    News

    Trials
    5ms
    Antisense RNAs (asRNAs) as key players in gallbladder cancer progression: a bioinformatics analysis. (PubMed, Gastroenterol Hepatol Bed Bench)
    Enrichment analysis of asRNAs with target mRNAs showed enrichment in biological regulation and developmental processes involved in the PI3K, p53, apoptosis, and VEGF signaling pathways. This study identified 14 asRNAs for the first time and showed that asRNAs targeting mRNAs strongly associated with tumor development in GBC through the PI3KCA and TP53 pathways.
    Journal
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    BBOX1 (Gamma-Butyrobetaine Hydroxylase 1) • BBOX1-AS1( BBOX1 Antisense RNA 1) • HAND2-AS1 (HAND2 Antisense RNA 1) • MIR1-1 (MicroRNA 1-1) • SLC2A1 (Solute Carrier Family 2 Member 1) • SOX21-AS1 (SOX21 Antisense Divergent Transcript 1) • DNAH17 (Dynein Axonemal Heavy Chain 17)
    over1year
    Is cross-species horizontal gene transfer responsible for gallbladder carcinogenesis. (PubMed, World J Surg Oncol)
    The results provide novel evidence supporting the hypothesis that differentially expressed asRNAs in GBC exhibit varying sequence similarity with bacterial, viral, and ancient human genomes, indicating a potential shared evolutionary origin. These non-coding genes are enriched with methylation and were found to be associated with cancer-related pathways, including the P53 and PI3K-AKT signaling pathways, suggesting their possible involvement in tumor development.
    Journal
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    BBOX1 (Gamma-Butyrobetaine Hydroxylase 1) • AFAP1-AS1 (AFAP1 Antisense RNA 1) • HMGA2 (High mobility group AT-hook 2) • BBOX1-AS1( BBOX1 Antisense RNA 1) • HAND2-AS1 (HAND2 Antisense RNA 1) • MIR1-1 (MicroRNA 1-1) • SLC2A1 (Solute Carrier Family 2 Member 1) • SOX21-AS1 (SOX21 Antisense Divergent Transcript 1) • DNAH17 (Dynein Axonemal Heavy Chain 17)
    3years
    P4 Cancer Screening: a multi-modal approach to screening for cervical cancer (USCAP 2023)
    It is likely that the future of cervical screening will involve a precision medicine-based approach. This study evaluates different approaches in a longitudinal study which has followed women through at least one round of cervical screening.
    MIR1-1 (MicroRNA 1-1)
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    BD Onclarity™ HPV Assay