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    BIOMARKER:

    miR-664a expression

    i
    Other names: MIR664A, MicroRNA 664a, Hsa-MiR-664a-3p, Hsa-MiR-664a-5p, MicroRNA 664, Hsa-Mir-664, MIR664A, Hsa-Mir-664a, Mir-664a, MIRN664, MIR664
    Entrez ID:
    100302234
    over2years
    miR-664b-3p inhibits colon cell carcinoma via negatively regulating Budding uninhibited by benzimidazole 3. (PubMed, Bioengineered)
    The study indicated that miR-664b-3p plays a significant role in colon cancer and could regulate the progression of colon cancer tumor growth by suppressing the expression of BUB3 protein. These findings provide a novel strategy to screen and treat colon cancer.
    Journal • IO biomarker
    |
    MMP2 (Matrix metallopeptidase 2) • CASP3 (Caspase 3) • CASP9 (Caspase 9) • MMP9 (Matrix metallopeptidase 9) • PCNA (Proliferating cell nuclear antigen) • MIR664A (MicroRNA 664a)
    |
    BCL2 expression • miR-664a expression
    over3years
    MicroRNA-664a-3p inhibits the proliferation of ovarian granulosa cells in polycystic ovary syndrome and promotes apoptosis by targeting BCL2A1. (PubMed, Ann Transl Med)
    The up-regulation of BCL2A1 promotes cell proliferation and reduces cell apoptosis by the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) pathway (both P<0.05). The up-regulation of miR-664a-3p inhibits the proliferation of KGN cells and increases apoptosis by down-regulating the expression of BCL2A1 and blocking the MAPK/ERK signaling pathway.
    Journal
    |
    BCL2 (B-cell CLL/lymphoma 2) • BCL2A1 (BCL2 Related Protein A1) • MIR664A (MicroRNA 664a)
    |
    BCL2 expression • BCL2A1 overexpression • miR-664a expression