^
    Contact us  to learn more about
    our Premium Content:  News alerts, weekly reports and conference planners
    BIOMARKER:

    miR-621 overexpression

    i
    Other names: MIR621, MicroRNA 621, Hsa-MiR-621, MIRN621
    Entrez ID:
    693206
    over3years
    MicroRNA-621 functions as a metastasis suppressor in colorectal cancer by directly targeting LEF1 and suppressing Wnt/β-catenin signaling. (PubMed, Life Sci)
    MiR-621 is a vital tumor suppressor in CRC and could be a promising anti-cancer therapeutic target.
    Journal
    |
    LEF1 (Lymphoid Enhancer Binding Factor 1) • MIR621 (MicroRNA 621)
    |
    LEF1 overexpression • miR-621 overexpression
    over4years
    Hsa-circ_0000064 accelerates the malignant progression of gastric cancer via sponging microRNA-621. (PubMed, Kaohsiung J Med Sci)
    Circ_0000064 can participate in the GC progression via modulating miR-621/SYF2 axis. This implies that circ_0000064 may be a new diagnosed biomarker or a new therapeutic target of GC.
    Journal
    |
    MIR621 (MicroRNA 621)
    |
    miR-621 overexpression
    almost5years
    miR-621 May Suppress Cell Proliferation via Targeting lncRNA SNHG10 in Acute Myeloid Leukemia. (PubMed, Cancer Manag Res)
    In addition, SNHG10 overexpression significantly promoted BMMNC proliferation, whereas miR-621 overexpression inhibited BMMNC proliferation and abolished the effect of SNHG10 overexpression on BMMNC proliferation. miR-621 targets SNHG10 to suppress cell proliferation in AML.
    Journal
    |
    MIR621 (MicroRNA 621)
    |
    miR-621 overexpression