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    BIOMARKER:

    miR-584 expression

    i
    Other names: MIR584, MicroRNA 584, Hsa-Mir-584, Hsa-MiR-584-5p, MIR584, MIRN584
    Entrez ID:
    693169
    1year
    Biomarker of Pulmonary Inflammatory Response in LUAD: miR-584-5p Targets RAB23 to Suppress Inflammation Induced by LPS in A549 Cells. (PubMed, Protein Pept Lett)
    Prognostic-related risk miR-584-5p can regulate the expression of RAB23 at both the mRNA and protein levels, thereby influencing the development of a PIR in LUAD. This will have significant implications for the clinical prognosis prediction and therapy decision-making of LUAD patients with PIR.
    Journal
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    MIR584 (MicroRNA 584)
    |
    miR-584 expression
    almost3years
    miR-584-5p Inhibits Osteosarcoma Progression by Targeting Connective Tissue Growth Factor. (PubMed, Cancer Biother Radiopharm)
    In addition, miR-584-5p inactivated Hippo pathway through CTGF in osteosarcoma. miR-584-5p inhibits osteosarcoma cell proliferation, migration, and invasion and promotes apoptosis by targeting CTGF, indicating that miR-584-5p acts as a promising diagnostic and predictive biomarker for osteosarcoma.
    Journal
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    MIR584 (MicroRNA 584) • MIR769 (MicroRNA 769) • CTGF (Connective tissue growth factor)
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    miR-584 expression
    4years
    circRNA 001306 enhances hepatocellular carcinoma growth by up-regulating CDK16 expression via sponging miR-584-5p. (PubMed, J Cell Mol Med)
    In vivo, overexpression of miR-584-5p or knockdown of circ_1306 could inhibit the expression of CDK16, and suppress tumour growth. Altogether, our findings suggested that circ_1306 could promoter HCC progress by miR-584-5p/CDK16 axis, which provided a novel marker for HCC diagnosis and treatment.
    Journal
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    MIR584 (MicroRNA 584)
    |
    CDK6 overexpression • miR-584 expression • CDK6 expression