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    BIOMARKER:

    miR-3651 expression

    i
    Other names: MIR3651, MicroRNA 3651, Hsa-Mir-3651, Hsa-MiR-3651, MIR3651
    Entrez ID:
    100500918
    2years
    miR-3651 Participates in the Growth Cycle of Hepatocellular Carcinoma Cells and Promotes the Malignant Metastasis via the PI3K/AKT/mTOR Signalling Pathway. (PubMed, J Oncol)
    Moreover, HepG2 presented notably downregulated autophagy-associated proteins, and the increase of miR-3651 further suppressed the autophagy process, but with the intervention of BEZ235, the impacts of miR-3651 were completely reversed. miR-3651 intensifies the growth and invasion of HCC cells through activating the PI3K/AKT/mTOR signalling pathway, which is probably a breakthrough in the future diagnosis and therapy of HCC.
    Journal
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    MIR3651 (MicroRNA 3651)
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    miR-3651 expression
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    dactolisib (RTB101)