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    BIOMARKER:

    miR-30b expression

    i
    Other names: miR-30b, MicroRNA 30b, Hsa-MiR-30b-5p, Hsa-MiR-30b-3p, Hsa-Mir-30b, MIR30B, Hsa-Mir-30-P2c, MIMAT0000420, MIMAT0004589, MI0000441, MIRN30B, Mir-30b, RF00131
    Entrez ID:
    407030
    Related biomarkers:
    Expression
    over2years
    MIR130B AS A NON-INVASIVE BIOMARKER FOR GASTRIC METAPLASIA, GASTRIC CANCER, AND OTHER GASTROINTESTINAL MALIGNANCIES. (DDW 2022)
    Conclusion : MIR130b is detectable and elevated in both the urine and serum of patients with GI cancers. MIR130b has potential as an early non-invasive diagnostic and therapeutic biomarker for GIM, GC, and other GI malignancies particularly resource-limited populations.
    MIR30B (MicroRNA 30b)
    |
    miR-30b expression
    over3years
    Triclosan-induced abnormal expression of miR-30b regulates fto-mediated mA methylation level to cause lipid metabolism disorder in zebrafish. (PubMed, Sci Total Environ)
    Consequently, we posit that TCS exposure caused zebrafish lipid-metabolism disorder by decreasing miR-30b expression to regulate fto-mediated mA methylation level. These findings contribute to our deep understanding of the underlying molecular mechanisms regarding contaminant-originating fatty liver and hepatocellular carcinoma, and also have practical significance in pollution warning and target therapy for related diseases.
    Journal
    |
    FASN (Fatty acid synthase) • MIR30B (MicroRNA 30b) • FTO (Alpha-Ketoglutarate-Dependent Dioxygenase FTO)
    |
    FTO expression • miR-30b expression • FTO overexpression