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    BIOMARKER:

    miR-25 underexpression

    i
    Other names: MIR25, MicroRNA 25, Hsa-Mir-25, Hsa-MiR-25-5p, Hsa-MiR-25-3p, MIRN25, Hsa-Mir-92-P2c, MIMAT0000081, MIMAT0004498, MI0000082, RF02020, MiR-25
    Entrez ID:
    407014
    4years
    Bevacizumab confers significant improvements in survival for ovarian cancer patients with low miR-25 expression and high miR-142 expression. (PubMed, J Ovarian Res)
    In conclusion, miR-25 expression correlates with a better PFS and OS in ovarian cancer. Patients with low miR-25 expression and high miR-142 expression could benefit from bevacizumab treatment significantly.
    Clinical • Journal
    |
    MIR142 (MicroRNA 142) • MIR25 (MicroRNA 25)
    |
    miR-142 overexpression • miR-25 underexpression
    |
    Avastin (bevacizumab)