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    BIOMARKER:

    miR-199a-5p expression

    i
    Other names: MIR199A1, MicroRNA 199a-1, Hsa-MiR-199a-5p, Hsa-MiR-199b-3p, Hsa-MiR-199a-3p, Hsa-Mir-199a-1, MIR199A1, Hsa-Mir-199-P2-V3, Hsa-Mir-199-P2-V2, Hsa-Mir-199-P2-V1, MiR-199a-3p, Mir-199a-1, MIR-199-S, MIRN199A1
    Entrez ID:
    406976
    1year
    Diagnostic Significance of hsa-miR-21-5p, hsa-miR-192-5p, hsa-miR-155-5p, hsa-miR-199a-5p Panel and Ratios in Hepatocellular Carcinoma on Top of Liver Cirrhosis in HCV-Infected Patients. (PubMed, Int J Mol Sci)
    Combining each of hsa-miR-21-5p, hsa-miR-155-5p, and hsa-miR-199a-5p with AFP made it possible to identify HCC development in the LC patients' cohort with higher sensitivity than using AFP alone. hsa-miR-21-5p/hsa-miR-199a-5p and hsa-miR-155-5p/hsa-miR-199a-5p ratios are potential HCC molecular markers for AFP-negative HCC patients. hsa-miR-21-5p was linked, clinically and via in silico proof, to insulin metabolism, inflammation, dyslipidemia, and tumorigenesis in the HCC patients' group as well as for an upregulated independent risk factor for the emergence of HCC from LC in the CHCV patients.
    Journal
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    AFP (Alpha-fetoprotein) • MIR155 (MicroRNA 155) • MIR21 (MicroRNA 21) • MIR192 (MicroRNA 192) • MIR199A1 (MicroRNA 199a-1) • MIR199A (MicroRNA 199a)
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    miR-155 expression • miR-199a-5p expression • miR-21 expression