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    BIOMARKER:

    miR-1247 overexpression

    i
    Other names: MIR1247, MicroRNA 1247, Hsa-MiR-1247-5p, Hsa-Mir-1247, MIMAT0005899, MIMAT0022721, MI0006382, Mir-1247, MIRN1247, MIR1247
    Entrez ID:
    100302145
    Associations

    News

    Trials
    2years
    Crucial role of hsa-mir-503, hsa-mir-1247, and their validation in prostate cancer. (PubMed, Aging (Albany NY))
    Herein, we demonstrated that hsa-mir-503 and hsa-mir-1247 could serve as new prognostic markers of PC, and hsa-mir-1247 had great potential to inhibit PC progression by suppressing the migration and invasion ability in vitro and in vivo.
    Journal
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    FGF2 (Fibroblast Growth Factor 2) • MIR503 (MicroRNA 503) • DUSP1 (Dual Specificity Phosphatase 1) • MIR1247 (MicroRNA 1247)
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    miR-1247 overexpression
    over2years
    Long noncoding RNA LINC01124 activates hepatocellular carcinoma cell proliferation, migration, and invasion by absorbing microRNA-1247-5p and overexpressing FOXO3. (PubMed, Oncol Res)
    In summary, LINC01124 plays a tumor-promoting role in HCC by regulating the miR-1247-5p-FOXO3 axis. The LINC01124-miR-1247-5p-FOXO3 pathway may provide a foundation for the identification of alternative therapies for HCC.
    Journal
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    FOXO3 (Forkhead box O3) • MIR1247 (MicroRNA 1247)
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    miR-1247 overexpression
    almost6years
    MiR-1247-5p Functions as a Tumor Suppressor in Human Astroglioma Cells by Targeting CDC14B. (PubMed, Ann Clin Lab Sci)
    These results suggest that miR-1247-5p functions as a tumor suppressor in human astroglioma U251 cells via the miR-1247-5p/CDC14B/p53 signaling axis. These findings indicate that miR-1247-5p has the potential to be a therapeutic target and diagnostic marker for gliomas.
    Journal
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    MIR1247 (MicroRNA 1247)
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    miR-1247 overexpression