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DRUG:

cam1615SS1

i
Other names: mesothelin-targeted TriKE, cam1615SS1, MSLN-targeted TriKE
Associations
Trials
Company:
GT Biopharma
Drug class:
NK cell stimulant, Mesothelin inhibitor, IL-15 stimulant
Related drugs:
Associations
Trials
over1year
A tri-specific killer engager against mesothelin targets NK cells towards lung cancer. (PubMed, Front Immunol)
Importantly, TriKE triggered NK cell responses from patients at all stages of disease and treatment, suggesting TriKE can enhance current therapies. These pre-clinical studies suggest mesothelin-targeted TriKE has the potential to overcome the immunosuppressive environment of NSCLC to treat disease.
Journal • Trispecific
|
MSLN (Mesothelin) • CD14 (CD14 Molecule) • IL15 (Interleukin 15)
|
cam1615SS1