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    DRUG:

    efgivanermin alfa (MEDI1873)

    i
    Other names: MEDI1873, MEDI 1873
    Associations

    News

    Trials
    Company:
    AstraZeneca
    Drug class:
    GITR agonist
    Related drugs:
    Associations

    News

    Trials
    over5years
    Safety and Clinical Activity of MEDI1873, a Novel GITR Agonist, in Advanced Solid Tumors. (PubMed, Clin Cancer Res)
    MEDI1873 showed acceptable safety up to 500 mg IV Q2W with pharmacodynamic activity, and prolonged SD in some patients. However, further development is not planned due to lack of demonstrated tumor response.
    Clinical • Journal
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    TNFA (Tumor Necrosis Factor-Alpha)
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    efgivanermin alfa (MEDI1873)