^
    3ms
    A Trial of HHPG-19K Injection and Auto-HHPG-19K Injection in Prevention of Chemotherapy-related Moderate to Severe Neutropenia of Patients With Nonmyeloid Malignancies (clinicaltrials.gov)
    P3, N=107, Not yet recruiting, Jiangsu HengRui Medicine Co., Ltd.
    New P3 trial
    |
    Pegylated rhG-CSF (mecapegfilgrastim)
    12ms
    Application of Mecapegfilgrastim for Peripheral Blood Hematopoietic Stem Cell Mobilization in Patients With Hematologic Neoplasms and Analysis of Predictors for Poor Mobilization (PubMed, Sichuan Da Xue Xue Bao Yi Xue Ban)
    To evaluate the efficacy of applying mecapegfilgrastim for peripheral blood hematopoietic stem cell (PBSC) mobilization in patients with hematologic neoplasms, and to investigate the influencing factors of PBSC collection. Furthermore, combined mobilization with plerixafor was feasible and effective. Patients with leukemia or lymphoma, anemia, and WBC<32×10 L before stem cell collection have a high probability of PBSC collection failure.
    Journal
    |
    CD34 (CD34 molecule)
    |
    Pegylated rhG-CSF (mecapegfilgrastim) • plerixafor
    1year
    Mecapegfilgrastim for the Prevention of Dalpiciclib -Induced Neutropenia in Advanced Breast Cancer (clinicaltrials.gov)
    P2, N=132, Recruiting, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Not yet recruiting --> Recruiting
    Enrollment open • Metastases
    |
    HER-2 (Human epidermal growth factor receptor 2)
    |
    HER-2 negative
    |
    tamoxifen • fulvestrant • letrozole • exemestane • AiRuiKang (dalpiciclib) • Pegylated rhG-CSF (mecapegfilgrastim)
    over1year
    Mecapegfilgrastim With Chemotherapy for Peripheral Blood Stem Cell Mobilization in MM and Lymphoma (clinicaltrials.gov)
    P2, N=120, Recruiting, Qiu Lugui | Not yet recruiting --> Recruiting
    Enrollment open • Combination therapy
    |
    CD34 (CD34 molecule)
    |
    cyclophosphamide • etoposide IV • Pegylated rhG-CSF (mecapegfilgrastim)
    almost2years
    Mecapegfilgrastim for the Prevention of Dalpiciclib -Induced Neutropenia in Advanced Breast Cancer (clinicaltrials.gov)
    P2, N=132, Not yet recruiting, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
    New P2 trial
    |
    HER-2 (Human epidermal growth factor receptor 2)
    |
    HER-2 negative
    |
    tamoxifen • fulvestrant • letrozole • exemestane • AiRuiKang (dalpiciclib) • Pegylated rhG-CSF (mecapegfilgrastim)
    2years
    Mecapegfilgrastim With Chemotherapy for Peripheral Blood Stem Cell Mobilization in MM and Lymphoma (clinicaltrials.gov)
    P2, N=120, Not yet recruiting, Qiu Lugui
    New P2 trial • Combination therapy
    |
    CD34 (CD34 molecule)
    |
    cyclophosphamide • etoposide IV • Pegylated rhG-CSF (mecapegfilgrastim)