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    BIOMARKER:

    MCT1 underexpression

    i
    Other names: SLC16A1, Solute Carrier Family 16 Member 1, Solute Carrier Family 16 Member 1 (Monocarboxylic Acid Transporter 1), Solute Carrier Family 16 (Monocarboxylic Acid Transporters) Member 1, Solute Carrier Family 16 (Monocarboxylate Transporter) Member 1, Monocarboxylate Transporter 1, MCT 1, MCT1, MCT1D, HHF7, MCT
    Entrez ID:
    6566
    Related biomarkers:
    Expression
    Associations

    News

    Trials
    over1year
    Construction of an M2 macrophage-related prognostic model in hepatocellular carcinoma. (PubMed, Front Oncol)
    The risk score was identified as a promising prognostic marker for TACE response, and the high-risk subgroup showed higher sensitivity to chemotherapeutic drugs (e.g., sorafenib, doxorubicin, cisplatin, and mitomycin) and immune checkpoint inhibitor (ICI) treatments. We identified 158 HCC-related M2 macrophage genes and constructed an M2 macrophage-related prognostic model. This study advances the understanding of the role of M2 macrophages in HCC and proposes new prognostic markers and therapeutic targets.
    Journal • Tumor mutational burden • IO biomarker
    |
    TMB (Tumor Mutational Burden) • MSI (Microsatellite instability) • ECM2 (Extracellular Matrix Protein 2)
    |
    MCT1 underexpression
    |
    cisplatin • sorafenib • doxorubicin hydrochloride • mitomycin