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GENE:

LZTFL1 (Leucine Zipper Transcription Factor Like 1)

i
Other names: LZTFL1, Leucine Zipper Transcription Factor Like 1, BBS17, Leucine Zipper Transcription Factor-Like Protein 1, Leucine Zipper Transcription Factor-Like 1
Associations
Trials
over1year
Genetic predisposition to milder forms of COVID-19 may provide some resilience to head and neck cancers. (PubMed, Front Oncol)
These genes include OAS1, LOC107985887, BCL11A, DPP9, LOC107984685, LINC02326, MUC4, NXPE3, IFNAR2, LZTFL1, LOC105372437, NAPSA, LOC105376622, LOC107986082, and SLC6A20. Our study emphasizes the protective role of the genetic liability to milder COVID-19 in reducing the risk of HNC while refuting a causal relationship between severe COVID-19 and HNC.
Journal
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MUC4 (Mucin 4, Cell Surface Associated) • IFNAR2 (Interferon Alpha And Beta Receptor Subunit 2) • NAPSA (Napsin A Aspartic Peptidase) • LZTFL1 (Leucine Zipper Transcription Factor Like 1)
almost2years
The role of telocytes and miR-21-5p in tumorigenicity and metastasis of breast cancer stem cells. (PubMed, Mol Biol Rep)
In our study, by gene/protein level analysis we demonstrated that telocytes may have the potential to reduce cancer metastasis through miR-21-5p in breast cancer progression and reduce EMT transition.
Journal • Cancer stem
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MIR21 (MicroRNA 21) • VIM (Vimentin) • ALDH1A1 (Aldehyde Dehydrogenase 1 Family Member A1) • CDH2 (Cadherin 2) • ABCC11 (ATP Binding Cassette Subfamily C Member 11) • SNAI1 (Snail Family Transcriptional Repressor 1) • LZTFL1 (Leucine Zipper Transcription Factor Like 1)
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VIM expression • miR-21 expression • ABCC11 expression
almost2years
Causality between COVID-19 and multiple myeloma: a two-sample Mendelian randomization study and Bayesian co-localization. (PubMed, Clin Exp Med)
This is the first study to use MR to explore the causality between different traits of COVID-19 and MM. The results of our two-way MR analysis found that SARS-CoV-2 infection and COVID-19 hospitalization increased the susceptibility of MM.
Journal
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MUC4 (Mucin 4, Cell Surface Associated) • MAPT (Microtubule Associated Protein Tau) • SLC22A3 (Solute Carrier Family 22 Member 3) • HLA-C (Major Histocompatibility Complex, Class I, C) • LZTFL1 (Leucine Zipper Transcription Factor Like 1)
over2years
Human leucocyte antigen-matched related haematopoietic stem cell transplantation using low-dose cyclophosphamide, fludarabine and thymoglobulin in children with severe aplastic anaemia. (PubMed, Br J Haematol)
Graft-versus-host disease (GVHD) prophylaxis included mycophenolate mofetil and calcineurin inhibitors...A low probability of GVHD was observed (one acute GVHD II and one mild chronic GVHD). These data highlight how HSCT using low-dose Cy as part of a fludarabine-based regimen is safe and effective in SAA/non-Fanconi anaemia IBMFS.
Journal
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ERCC6 (Excision repair cross-complementation group 6) • ANKRD26 (Ankyrin Repeat Domain Containing 26) • TINF2 (TERF1 Interacting Nuclear Factor 2) • LZTFL1 (Leucine Zipper Transcription Factor Like 1)
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cyclophosphamide • fludarabine IV