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    GENE:

    LRRC47 (Leucine-rich repeat-containing protein 47)

    i
    Other names: LRRC47, Leucine Rich Repeat Containing 47, Leucine-Rich Repeat-Containing Protein 47, KIAA1185, RP1-286D6.3
    Associations

    News

    Trials
    over2years
    Complementary analysis of proteome-wide proteomics reveals changes in RNA binding protein-profiles during prostate cancer progression. (PubMed, Cancer Rep (Hoboken))
    In this work, we recognized significant molecular alterations in RBP profiles during development and evolution of prostate cancer. Our study further indicates several functionally significant RBPs warranting further investigation for their functions and possible targetability in prostate cancer.
    Journal
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    EIF4A3 (Eukaryotic Translation Initiation Factor 4A3) • HNRNPH1 (Heterogeneous Nuclear Ribonucleoprotein H1) • LRRC47 (Leucine-rich repeat-containing protein 47)
    over2years
    The Role of the Dysregulation of Long Non-Coding and Circular RNA Expression in Medulloblastoma: A Systematic Review. (PubMed, Cancers (Basel))
    Among the circRNAs, the upregulation of circSKA3 and its functional impact in MB cell lines were the most consistent results, so this circRNA could be considered a potential biomarker in MB. Additional validation is required for many deregulated lncRNAs and circRNAs; therefore, further studies are warranted.
    Review • Journal
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    LRRC47 (Leucine-rich repeat-containing protein 47)
    4years
    High expression of PDZ-binding kinase is correlated with poor prognosis and immune infiltrates in hepatocellular carcinoma. (PubMed, World J Surg Oncol)
    High expression of PBK is significantly correlated with poor survival and immune infiltrates in hepatocellular carcinoma. Our study suggests that PBK can be used as a biomarker of poor prognosis and potential immune therapy target in hepatocellular carcinoma.
    Journal
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    ARAF (A-Raf Proto-Oncogene) • PBK (PDZ Binding Kinase) • LRRC47 (Leucine-rich repeat-containing protein 47)