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DRUG:

LMB-2

i
Other names: LMB-2, Anti-Tac(Fv)-PE38, Anti-Tac(Fv)-PE38 (LMB-2) Immunotoxin
Associations
Company:
National Cancer Institute
Drug class:
IL-2R antagonist
Associations
1year
LMB-2 to Treat Hairy Cell Leukemia (clinicaltrials.gov)
P2, N=15, Completed, National Cancer Institute (NCI) | Active, not recruiting --> Completed | Trial completion date: Mar 2024 --> Dec 2022
Trial completion • Trial completion date
|
BRAF (B-raf proto-oncogene)
|
IL2RA positive
|
LMB-2
1year
Phase II Trial of LMB-2, Fludarabine and Cyclophosphamide for Adult T-Cell Leukemia (clinicaltrials.gov)
P1/2, N=18, Completed, National Cancer Institute (NCI) | Active, not recruiting --> Completed | Phase classification: P2 --> P1/2
Trial completion • Phase classification
|
cyclophosphamide • Campath (alemtuzumab) • fludarabine IV • LMB-2
over2years
LMB-2 to Treat Hairy Cell Leukemia (clinicaltrials.gov)
P2, N=15, Active, not recruiting, National Cancer Institute (NCI) | Trial completion date: Mar 2022 --> Mar 2024
Trial completion date
|
BRAF (B-raf proto-oncogene)
|
IL2RA positive
|
LMB-2
over3years
LMB-2 to Treat Hairy Cell Leukemia (clinicaltrials.gov)
P2, N=15, Active, not recruiting, National Cancer Institute (NCI) | Trial completion date: Mar 2021 --> Mar 2022
Clinical • Trial completion date
|
BRAF (B-raf proto-oncogene)
|
IL2RA positive
|
LMB-2