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DRUG:

LM-101

i
Other names: LM-101, LM 101, LM101
Associations
Trials
Company:
LaNova Medicines Limited
Drug class:
SIRPA antagonist
Associations
Trials
3d
LM101-01-103: A Phase I/II Study of LM-101 Injection in Patients With Advanced Malignant Tumors (clinicaltrials.gov)
P1/2, N=139, Recruiting, LaNova Medicines Limited | Suspended --> Recruiting | Trial completion date: Aug 2025 --> Jan 2028 | Trial primary completion date: Dec 2024 --> Jan 2027
Enrollment open • Trial completion date • Trial primary completion date • Metastases
|
Rituxan (rituximab) • Loqtorzi (toripalimab-tpzi) • LM-101
12ms
Trial completion date • Trial primary completion date • Combination therapy • Metastases
|
Rituxan (rituximab) • Loqtorzi (toripalimab-tpzi) • Enweida (envafolimab) • LM-101
1year
A Phase I/II Study of LM-101 Injection in Patients With Advanced Malignant Tumors (clinicaltrials.gov)
P1/2, N=145, Suspended, LaNova Medicines Limited | Recruiting --> Suspended
Trial suspension • Combination therapy • Metastases
|
Rituxan (rituximab) • Loqtorzi (toripalimab-tpzi) • Enweida (envafolimab) • LM-101
almost2years
A Phase I/II Study of LM-101 Injection in Patients With Advanced Malignant Tumors (clinicaltrials.gov)
P1/2, N=145, Recruiting, LaNova Medicines Limited | Not yet recruiting --> Recruiting
Enrollment open • Combination therapy • IO biomarker • Metastases
|
PD-L1 (Programmed death ligand 1) • CD8 (cluster of differentiation 8) • CD163 (CD163 Molecule) • CD68 (CD68 Molecule)
|
Rituxan (rituximab) • Loqtorzi (toripalimab-tpzi) • Enweida (envafolimab) • LM-101
2years
New P1/2 trial • Combination therapy • IO biomarker • Metastases
|
PD-L1 (Programmed death ligand 1) • CD8 (cluster of differentiation 8) • CD163 (CD163 Molecule) • CD68 (CD68 Molecule)
|
Rituxan (rituximab) • Loqtorzi (toripalimab-tpzi) • Enweida (envafolimab) • LM-101