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DRUG:

Lipoplatin (cisplatin liposomal)

Associations
Trials
Company:
Regulon
Drug class:
DNA cross linking agent
Associations
Trials
over2years
Comparison of Cytotoxic and Ototoxic Effects of Lipoplatin and Cisplatin in Neuroblastoma In Vivo Tumor Model. (PubMed, J Int Adv Otol)
For the treatment of neuroblastoma, the use of lipoplatin seems to be beneficial in reducing side effects of cisplatin. We recommend that the mechanism of these properties of lipoplatin should be evaluated in further studies.
Preclinical • Journal
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NOS2 (Nitric Oxide Synthase 2) • SOD2 (Superoxide Dismutase 2)
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PTGS2 mutation
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Lipoplatin (cisplatin liposomal)