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    GENE:

    LINC01871 (Long Intergenic Non-Protein Coding RNA 1871)

    i
    Other names: LINC01871, Long Intergenic Non-Protein Coding RNA 1871, NONHSAG026917.2, HSALNG0012783, LINC01871
    Associations

    News

    Trials
    7ms
    N7-methylguanosine (m7G) modification in breast cancer: clinical significances and molecular mechanisms. (PubMed, Cancer Cell Int)
    These novel insights indicate that m7G modification and its regulators hold significant potential for future clinical applications in the diagnosis and treatment of BC. In the future, how to apply m7G modifications to identify the implementation of clinically personalized BC treatment needs to be further explored.
    Review • Journal
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    MIR7 (MicroRNA 7) • MIR139 (MicroRNA 139) • LINC01871 (Long Intergenic Non-Protein Coding RNA 1871) • METTL1 (Methyltransferase 1, TRNA Methylguanosine) • WDR4 (WD Repeat Domain 4)
    12ms
    LINC01871 facilitates cervical cancer cell migration and immune escape by targeting miR-873-3p/MAP3K2 axis. (PubMed, Kaohsiung J Med Sci)
    Furthermore, MAP3K2 overexpression rescued the inhibitory effects of LINC01871 silencing on the malignant behaviors of CC cells. In conclusion, LINC01871 facilitates CC metastasis by driving EMT and modulating the immune response via the miR-873-3p/MAP3K2/MAPK signaling pathway.
    Journal
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    LINC01871 (Long Intergenic Non-Protein Coding RNA 1871)
    over1year
    An Aging-Related lncRNA Signature Establishing for Breast Cancer Prognosis and Immunotherapy Responsiveness Prediction. (PubMed, Pharmgenomics Pers Med)
    Of note, the qRT-PCR analysis validated that these 6 AG-lncs expressed quite differentially in BC tissues at various clinical stages. The risk signature of 6 AG-lncs might offer a novel prognostic biomarker and promisingly enhance BC immunotherapy's effectiveness.
    Journal • IO biomarker
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    TNFRSF14 (TNF Receptor Superfamily Member 14) • MAPT (Microtubule Associated Protein Tau) • OTUD6B (OTU Deubiquitinase 6B) • LINC01871 (Long Intergenic Non-Protein Coding RNA 1871) • MAPT-AS1 (MAPT Antisense RNA 1) • OTUD6B-AS1 (OTUD6B Antisense RNA 1)
    2years
    Identification of AP002498.1 and LINC01871 as prognostic biomarkers and therapeutic targets for distant metastasis of colorectal adenocarcinoma. (PubMed, Cancer Med)
    The DElncRNA AP002498.1 and the LINC01871/miR-4644 and miR-185-5p/GNLY axes were identified as being closely associated with distant metastasis and could represent independent prognostic biomarkers or therapeutic targets in colorectal adenocarcinoma.
    Journal • IO biomarker
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    CXCL10 (Chemokine (C-X-C motif) ligand 10) • IDO1 (Indoleamine 2,3-dioxygenase 1) • CXCL9 (Chemokine (C-X-C motif) ligand 9) • MUC5B (Mucin 5B, Oligomeric Mucus/Gel-Forming) • NOS2 (Nitric Oxide Synthase 2) • miR-185 (MicroRNA 185) • GBP4 (Guanylate Binding Protein 4) • LINC01871 (Long Intergenic Non-Protein Coding RNA 1871) • SERPINA1 (Serpin Family A Member 1) • MIR4644 (MicroRNA 4644)
    over2years
    Necroptosis-related LncRNAs in skin cutaneous melanoma: evaluating prognosis, predicting immunity, and guiding therapy. (PubMed, BMC Cancer)
    Our prognostic model can independently predict the survival of melanoma patients while providing a basis for the subsequent investigation of necroptosis in melanoma and a new perspective on the clinical diagnosis and treatment of melanoma.
    Journal • IO biomarker
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    HLA-DQB1 (Major Histocompatibility Complex, Class II, DQ Beta 1) • IRF2 (Interferon Regulatory Factor 2) • LINC01871 (Long Intergenic Non-Protein Coding RNA 1871)
    over2years
    Machine learning-based signature of necrosis-associated lncRNAs for prognostic and immunotherapy response prediction in cutaneous melanoma and tumor immune landscape characterization. (PubMed, Front Endocrinol (Lausanne))
    Thus, the low-risk group would have a more sensitive response to immunotherapy. This risk score signature could be used to divide CM patients into low- and high-risk groups, and facilitate treatment strategy decision making that immunotherapy is more suitable for those in low-risk group, providing a new sight for CM prognostic evaluation.
    Journal • IO biomarker • Machine learning
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    LINC00665 (Long Intergenic Non-Protein Coding RNA 665) • LINC01871 (Long Intergenic Non-Protein Coding RNA 1871)
    almost3years
    LncRNA LINC01871 sponging miR-142-3p to modulate ZYG11B promotes the chemoresistance of colorectal cancer cells by inducing autophagy. (PubMed, Anticancer Drugs)
    LINC01871/miR-142-3p/ ZYG11B axis regulates the chemoresistance of CRCs by inducing autophagy.
    Journal
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    HMGB1 (High Mobility Group Box 1) • MIR142 (MicroRNA 142) • LINC01871 (Long Intergenic Non-Protein Coding RNA 1871)
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    5-fluorouracil