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    BIOMARKER:

    LINC00667 overexpression

    over2years
    LncRNA LINC00667 gets involved in clear cell renal cell carcinoma development and chemoresistance by regulating the miR-143-3p/ZEB1 axis. (PubMed, Aging (Albany NY))
    LINC00667 is up-regulated in ccRCC and enhances the ZEB1 expression by targeting miR-143-3p, which in turn accelerates ccRCC progression and induces chemoresistance.
    Journal
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    MIR143 (MicroRNA 143) • ZEB1 (Zinc Finger E-box Binding Homeobox 1) • LINC00667 (Long Intergenic Non-Protein Coding RNA 667)
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    LINC00667 overexpression • ZEB1 expression • miR-143-3p overexpression