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    BIOMARKER:

    LINC00461 overexpression

    Associations

    News

    Trials
    over3years
    LINC00461 Regulates the Recurrence of Large B Cell Lymphoma through the miR-411-5p/BNIP3 Pathway. (PubMed, Evid Based Complement Alternat Med)
    The inhibition of LINC00461 or overexpression of miR-411-5p reduced the expression of BNIP3 protein, thereby inducing apoptosis at the in vivo and in vitro levels. LINC00461 may induce miR-411-5p to "sponge," thereby increasing the expression of BNIP3 protein, and exerting the function of inhibiting apoptosis and promoting DLBCL recurrence.
    Journal • IO biomarker
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    BCL2 (B-cell CLL/lymphoma 2) • BNIP3 (BCL2 Interacting Protein 3) • LINC00461 (Long Intergenic Non-Protein Coding RNA 461)
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    LINC00461 overexpression