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DRUG:

YTS104

i
Other names: YTS104, S104, LILRB4 STAR-T
Associations
Company:
Beijing Qingyi Taike Pharma, BriSTAR Immunotech
Drug class:
ILT-3 inhibitor
Associations
6ms
LILRB4 represents a promising target for immunotherapy by dual targeting tumor cells and myeloid-derived suppressive cells in multiple myeloma. (PubMed, Haematologica)
In conclusion, our study elucidates that LILRB4 is an ideal biomarker and promising immunotherapy target for high-risk MM. LILRB4-STAR-T cell immunotherapy is promising against tumor cells and immunosuppressive tumor microenvironment in MM.
Journal • IO biomarker • Tumor cell
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LILRB4 (Leukocyte Immunoglobulin Like Receptor B4)
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YTS104
over1year
YTS104 Cell Injection for the Treatment of Relapsed or Refractory Multiple Myeloma (clinicaltrials.gov)
P1, N=8, Not yet recruiting, Institute of Hematology & Blood Diseases Hospital
New P1 trial
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LILRB4 (Leukocyte Immunoglobulin Like Receptor B4)
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cyclophosphamide • YTS104