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    BIOMARKER:

    LGALS3 elevation

    i
    Other names: LGALS3, Advanced Glycation End-Product Receptor 3, Lectin, Galactoside-Binding, Soluble, 3, Carbohydrate-Binding Protein 35, Galactose-Specific Lectin 3, Laminin-Binding Protein, IgE-Binding Protein, 35 KDa Lectin, Lectin L-29, Galectin-3, GALBP, GALIG, MAC2, Epididymis Secretory Sperm Binding Protein, Galactoside-Binding Protein, MAC-2 Antigen, Mac-2 Antigen, LGALS2, CBP 35, CBP35, MAC-2, Gal-3, GAL3, L-31, L31
    Entrez ID:
    3958
    Related biomarkers:
    Expression
    7ms
    High LGALS3 expression induced by HCP5/hsa-miR-27b-3p correlates with poor prognosis and tumor immune infiltration in hepatocellular carcinoma. (PubMed, Cancer Cell Int)
    Our findings indicated that the upregulation of LGALS3 via the HCP5/hsa-miR-27b-3p axis is associated with unfavorable prognosis and increased tumor immune infiltration in HCC.
    Journal
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    LGALS3 (Galectin 3) • MIR27B (MicroRNA 27b)
    |
    LGALS3 elevation
    9ms
    Targeting Galectin 3 illuminates its contributions to the pathology of uterine serous carcinoma. (PubMed, Br J Cancer)
    These findings suggest inhibiting Gal3 may benefit USC patients.
    Journal
    |
    LGALS3 (Galectin 3)
    |
    LGALS3 elevation
    9ms
    LGALS3BP is a novel and potential biomarker in clear cell renal cell carcinoma. (PubMed, Aging (Albany NY))
    After LGALS3BP knockdown, the proliferation of 769-P and 786-O cells decreased. The present findings show that LGALS3BP is critical for ccRCC cell proliferation and may be a potential target and biomarker for ccRCC.
    Journal
    |
    CD4 (CD4 Molecule) • FGF2 (Fibroblast Growth Factor 2) • LGALS3 (Galectin 3) • LGALS3BP (Lectin galactoside-binding soluble 3-binding protein)
    |
    LGALS3 elevation
    10ms
    Impaired bisecting GlcNAc reprogrammed M1 polarization of macrophage. (PubMed, Cell Commun Signal)
    Overall, our study highlights the impact of glycosylation on macrophage polarization and suggests the potential of engineered macrophages via glycosylated modification. Video Abstract.
    Journal
    |
    LGALS3 (Galectin 3) • LGALS3BP (Lectin galactoside-binding soluble 3-binding protein)
    |
    LGALS3 elevation