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    BIOMARKER:

    LAMP3 overexpression

    i
    Other names: LAMP3, Lysosomal Associated Membrane Protein 3, TSC403, DCLAMP, DC-LAMP, CD208, LAMP, DC-Lysosome-Associated Membrane Glycoprotein, Lysosome-Associated Membrane Glycoprotein 3, Lysosomal-Associated Membrane Protein 3, DC LAMP, LAMP-3, Protein TSC403, CD208 Antigen
    Entrez ID:
    27074
    Related biomarkers:
    Expression
    Others
    1m
    Lysosome-Associated Membrane Protein-3 (LAMP3) Expression in Oral Squamous Cell Carcinoma and Its Relationship With Clinicopathological Parameters: A Cross-Sectional Study. (PubMed, Cureus)
    High LAMP3 expression in poorly differentiated OSCC might indicate that it plays a pivotal role in oncogenic cell transformation. Our results indicate that LAMP3 may be a predictive marker for poor prognosis in OSCC.
    Observational data • Journal
    |
    LAMP3 (Lysosomal Associated Membrane Protein 3)
    |
    LAMP3 expression • LAMP3 overexpression
    11ms
    LAMP3 is a potent uterine corpus endometrial carcinoma prognostic biomarker associated with immune behavior. (PubMed, Aging (Albany NY))
    LAMP3 is a formidable biomarker for UCEC and could be a prospective candidate for the diagnosis, treatment and prognostic assessment of UCEC.
    Journal
    |
    LAMP3 (Lysosomal Associated Membrane Protein 3) • ABCA3 (ATP Binding Cassette Subfamily A Member 3)
    |
    LAMP3 expression • LAMP3 overexpression
    11ms
    A pan-cancer analysis of prognostic significance and immunological role of lysosomal-associated membrane protein 3. (PubMed, J Cell Mol Med)
    There is a significant correlation between the expression of LAMP3 and PD-L1.Our study elucidates that LAMP3 has different expression patterns and genetic alteration patterns in different tumours. It is a potential biomarker for immune-related cancer diagnosis, prognosis and efficacy prediction.
    Journal • BRCA Biomarker • PD(L)-1 Biomarker • IO biomarker • Pan tumor
    |
    PD-L1 (Programmed death ligand 1) • BRCA (Breast cancer early onset) • LAMP3 (Lysosomal Associated Membrane Protein 3)
    |
    PD-L1 expression • LAMP3 expression • LAMP3 overexpression
    1year
    Curcumin inhibits the development of colorectal cancer via regulating the USP4/LAMP3 pathway. (PubMed, Naunyn Schmiedebergs Arch Pharmacol)
    In addition, curcumin obviously restrained tumor growth in mice through downregulating USP4 and LAMP3 expression. These data indicated that curcumin exert the anti-tumor effects on the development of colorectal cancer through modulating the USP4/LAMP3 pathway.
    Journal
    |
    MMP2 (Matrix metallopeptidase 2) • BAX (BCL2-associated X protein) • LAMP3 (Lysosomal Associated Membrane Protein 3)
    |
    BAX expression • LAMP3 expression • LAMP3 overexpression