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    BIOMARKER:

    KLK4 expression

    i
    Other names: KLK4, Kallikrein Related Peptidase 4, KLK-L1, EMSP1, PSTS, Enamel Matrix Serine Proteinase 1, PRSS17, EMSP, Kallikrein-Like Protein 1, Serine Protease 17, Kallikrein-4, Prostase, Kallikrein 4 (Prostase, Enamel Matrix, Prostate), Enamel Matrix Serine Protease 1, Androgen-Regulated Message 1, Kallikrein, AI2A1, ARM1
    Entrez ID:
    9622
    over2years
    MDPK67b in Patients With Prostate Cancer (clinicaltrials.gov)
    P1, N=15, Recruiting, Med Discovery SA | Trial completion date: Aug 2023 --> Jun 2024 | Trial primary completion date: Aug 2023 --> Jun 2024
    Trial completion date • Trial primary completion date
    |
    AR (Androgen receptor) • KLK2 (Kallikrein-related peptidase 2)
    |
    KLK2 expression • KLK4 expression
    over2years
    KLK4 promotes proliferation, migration, invasion, and pro-angiogenesis of endometrial stromal cells via regulation of regulation of BDNF production in endometriosis. (PubMed, Am J Pathol)
    Together, our findings demonstrate the promotive role of KLK4 in endometriosis development. In addition, our study provides a new insight that KLK4 might be a potential therapeutic target and prognostic marker for endometriosis patients.
    Journal • Stroma
    |
    BDNF (Brain Derived Neurotrophic Factor)
    |
    KLK4 expression