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our Premium Content: News alerts, weekly reports and conference plannersDRUG:
Khapzory (levoleucovorin)
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News alerts, weekly reports and conference planners
Company:
Assertio, Aurobindo
Drug class:
Folate analog
Related drugs:
5ms
BREAKWATER: A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer (clinicaltrials.gov)
P3, N=816, Active, not recruiting, Pfizer | Recruiting --> Active, not recruiting
Enrollment closed • Metastases
|
BRAF (B-raf proto-oncogene)
|
Avastin (bevacizumab) • Erbitux (cetuximab) • 5-fluorouracil • capecitabine • Braftovi (encorafenib) • oxaliplatin • irinotecan • leucovorin calcium • Khapzory (levoleucovorin) • levoleucovorin calcium
almost4years
BRAF V600E-mutant Colorectal Cancer Study of Encorafenib Taken With Cetuximab Plus or Minus Chemotherapy (BREAKWATER) (clinicaltrials.gov)
P3, N=930, Recruiting, Pfizer | Not yet recruiting --> Recruiting
Clinical • Enrollment open
|
BRAF (B-raf proto-oncogene) • MSI (Microsatellite instability)
|
BRAF V600E • BRAF V600
|
Avastin (bevacizumab) • Erbitux (cetuximab) • 5-fluorouracil • capecitabine • Braftovi (encorafenib) • oxaliplatin • irinotecan • leucovorin calcium • Khapzory (levoleucovorin)
4years
BRAF V600E-mutant Colorectal Cancer Study of Encorafenib Taken With Cetuximab Plus or Minus Chemotherapy (BREAKWATER) (clinicaltrials.gov)
P3, N=930, Not yet recruiting, Pfizer
Clinical • New P3 trial
|
BRAF (B-raf proto-oncogene) • MSI (Microsatellite instability)
|
BRAF V600E • BRAF V600
|
Avastin (bevacizumab) • Erbitux (cetuximab) • 5-fluorouracil • capecitabine • Braftovi (encorafenib) • oxaliplatin • irinotecan • leucovorin calcium • Khapzory (levoleucovorin)
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