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    BIOMARKER:

    KDR V297I

    i
    Other names: KDR, CD309, FLK1, VEGFR, VEGFR2, Kinase insert domain receptor (a type III receptor tyrosine kinase)
    Entrez ID:
    3791
    Related biomarkers:
    Expression
    Mutation
    CNA
    Others
    over1year
    KRAS Mutations Are Associated with Shortened Survival in Patients with Epithelioid Malignant Pleural Mesothelioma. (PubMed, Cancers (Basel))
    Conversely, the presence of KDR single nucleotide polymorphism p.V297I (rs2305948) resulted in a favorable variable for survival (NR versus 23.4 months; p = 0.026). With the intrinsic limitations of a small number of cases and patient heterogeneity, results of this study contribute to the characterization of the mutation profile of MPM and the impact of selected somatic mutations, and possibly KDR polymorphism, on prognosis.
    Journal
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    KRAS (KRAS proto-oncogene GTPase) • KDR (Kinase insert domain receptor)
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    KRAS mutation • KRAS wild-type • RAS wild-type • KDR V297I