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    BIOMARKER:

    JAML overexpression

    i
    Other names: JAML, Junction Adhesion Molecule Like, Adhesion Molecule Interacting With CXADR Antigen 1, Adhesion Molecule, Interacts With CXADR Antigen 1, Junctional Adhesion Molecule-Like, AMICA1, AMICA, Gm638, Dendritic-Cell Specific Protein CREA7-1, Dendritic-Cell Specific Protein CREA7-4, Dendritic Cell-Specific Protein CREA7-1, Adhesion Molecule AMICA, CREA7-1, CREA7-4
    Entrez ID:
    120425
    almost2years
    JAML inhibits colorectal carcinogenesis by modulating the tumor immune microenvironment. (PubMed, In Vitro Cell Dev Biol Anim)
    CXADR can inhibit the proliferation of cancer cells and promote the apoptosis. JAML agonist can effectively treat colorectal cancer by regulating CD8+ T cells.
    Journal • PD(L)-1 Biomarker • IO biomarker
    |
    CD8 (cluster of differentiation 8) • PD-1 (Programmed cell death 1) • HAVCR2 (Hepatitis A Virus Cellular Receptor 2) • CXADR (CXADR Ig-Like Cell Adhesion Molecule)
    |
    CD8 overexpression • CD8 expression • HAVCR2 expression • JAML overexpression