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BIOMARKER:
JAK2 rearrangement
i
Other names:
JTK10, THCYT3, JAK2, Janus Kinase 2, Tyrosine-Protein Kinase JAK2, JAK-2
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Entrez ID:
3717
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
CRLF2 rearrangement + JAK2 fusion (1)
HMGA1 deletion+ JAK2 V617F (1)
IGH-CRLF2 fusion + JAK2 GPInsR683 (1)
IGH-CRLF2 fusion + JAK2 R867Q (1)
IGH-CRLF2 fusion + JAK2 R683G (1)
JAK2 mutation + MSI-H/dMMR (1)
P2RY8-CRLF2 fusion + JAK2 QGinsR683 (1)
PD-L1 expression + JAK2 mutation (1)
PD-L1 expression + STK11 mutation + JAK2 mutation (1)
RNPC3‐JAK2 fusion + Chr t(1;9)(p13;p22) (1)
HMGA1 deletion+ JAK2 V617 (0)
CRLF2 rearrangement + JAK2 fusion (1)
HMGA1 deletion+ JAK2 V617F (1)
IGH-CRLF2 fusion + JAK2 GPInsR683 (1)
IGH-CRLF2 fusion + JAK2 R867Q (1)
IGH-CRLF2 fusion + JAK2 R683G (1)
JAK2 mutation + MSI-H/dMMR (1)
P2RY8-CRLF2 fusion + JAK2 QGinsR683 (1)
PD-L1 expression + JAK2 mutation (1)
PD-L1 expression + STK11 mutation + JAK2 mutation (1)
RNPC3‐JAK2 fusion + Chr t(1;9)(p13;p22) (1)
HMGA1 deletion+ JAK2 V617 (0)
›
Associations
News
Trials
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Latest
3years
Ruxolitinib in Treating Patients With Hypereosinophilic Syndrome or Primary Eosinophilic Disorders (clinicaltrials.gov)
P2, N=25, Recruiting, Jason Robert Gotlib | Not yet recruiting --> Recruiting | Trial completion date: Jun 2024 --> Oct 2023 | Trial primary completion date: Apr 2021 --> Apr 2023
3 years ago
Clinical • Enrollment open • Trial completion date • Trial primary completion date
|
JAK2 (Janus kinase 2) • ETV6 (ETS Variant Transcription Factor 6) • PCM1 (Pericentriolar Material 1)
|
JAK2 mutation • JAK2 rearrangement
|
Jakafi (ruxolitinib)
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