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BIOMARKER:

IL2RA-L

i
Other names: IL2RA, CD25, IDDM10, IL2R
Entrez ID:
Related biomarkers:
over1year
Low CD25 Expression is Associated with Older Age and Poorer Prognosis in Patients with ALK+ Anaplastic Large Cell Lymphoma (USCAP 2023)
Most cases of ALK+ ALCL highly express CD25 indicating that CD25 is a potential therapeutic target for ALCL patients. In this study, low CD25 expression identified a subset of ALK+ ALCL cases associated with older patient age, thrombocytopenia and shorter OS. These data suggest that assessing CD25 in ALK+ ALCL may be useful for guiding targeted therapy and in predicting prognosis of patients with ALK+ ALCL.
Clinical
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ALK (Anaplastic lymphoma kinase) • CD8 (cluster of differentiation 8) • TNFRSF8 (TNF Receptor Superfamily Member 8) • IL2RA (Interleukin 2 receptor, alpha) • CD5 (CD5 Molecule) • CD2 (CD2 Molecule)
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TNFRSF8 expression • IL2RA expression • CD5 positive • IL2R overexpression • IL2RA-L