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    BIOMARKER:

    IGF1 rs2946834

    i
    Other names: IGF1, IGF-I, IGF1A, IGFI, Insulin-like growth factor 1, somatomedin C
    Entrez ID:
    3479
    Related biomarkers:
    Expression
    Mutation
    Others
    over2years
    Mammographic breast density and IGF-1 gene polymorphisms rs1520220, rs2946834 and rs6219 in Polish women. (PubMed, Contemp Oncol (Pozn))
    In the present study no relationship was detected between rs6219 and rs2946834 polymorphism and mammographic breast density. The results suggest that the rs1520220 polymorphism of the IGF-1 gene plays an important role in the occurrence of increased mammographic breast density.
    Clinical • Journal
    |
    IGF1 (Insulin-like growth factor 1)
    |
    IGF1 rs2946834
    over3years
    Single nucleotide polymorphisms of insulin-like growth factor gene and mammographic breast density. (PubMed, Prz Menopauzalny)
    The results obtained in the course of the analysis indicate that polymorphisms rs1520220, rs2946834, rs5747694 gene IGF-1 are associated with the occurrence of breast cancer but not with increased mammographic density. Summing up, the association between the polymorphisms of IGF-1 and the risk of developing breast cancer is independent of mammographic density.
    Journal
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    IGF1 (Insulin-like growth factor 1)
    |
    IGF1 rs2946834
    over3years
    Insulin-Like Growth Factor 1 (IGF1) Pathway Member Polymorphisms Are Associated with Risk and Prognosis of Chondrosarcoma. (PubMed, Med Sci Monit)
    IGF1R rs2016347 polymorphisms were associated with the risk of lung metastasis of CHS. The IGF1 pathway members do not appear to be involved in the tumorigenesis of CHS.
    Journal
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    IGF1 (Insulin-like growth factor 1) • IGF2 (Insulin-like growth factor 2) • IGFBP3 (Insulin-like growth factor binding protein 3)
    |
    IGF1 elevation • IGF1 rs2016347 • IGF1 rs2946834