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    BIOMARKER:

    ICAM1 elevation

    i
    Other names: ICAM1, BB2, CD54, Intercellular adhesion molecule 1
    Entrez ID:
    3383
    Related biomarkers:
    Expression
    almost2years
    ICAM-1 on Breast Cancer Cells Suppresses Lung Metastasis but Is Dispensable for Tumor Growth and Killing by Cytotoxic T Cells. (PubMed, Front Immunol)
    Collectively, our results are a first indication that ICAM-1 expressed by metastatic breast cancer cells that expand inside the lung vasculature is involved in innate rather than in adaptive cancer cell killing. This is also a first indication that the breast tumor expression of ICAM-1 is not required for CTL-mediated killing but can function as a suppressor of intravascular breast cancer metastasis to lungs.
    Journal
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    ICAM1 (Intercellular adhesion molecule 1)
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    ICAM1 elevation
    over2years
    Metastasis prognostic factors and cancer stem cell-related transcription factors associated with metastasis induction in canine metastatic mammary gland tumors. (PubMed, J Vet Sci)
    Consistent expression patterns of all metastasis-related factors showing elevation in ICAM-1, PRR14, VEGF, hnRNP H, Oct4, Sox2, and Nanog, but decreases in RPL4 levels occurred in canine MGT tissues, which was associated with metastasis. Thus, these cancer prognostic metastasis factors and TFs of cancer stem cells, except for E-cadherin and HPRT1, can be used as reliable metastasis factors for canine MGT and therapeutic strategy.
    Journal
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    CDH1 (Cadherin 1) • ICAM1 (Intercellular adhesion molecule 1) • SOX2 • POU5F1 (POU Class 5 Homeobox 1) • NANOG (Nanog Homeobox)
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    ICAM1 elevation