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    GENE:

    HYDIN (HYDIN Axonemal Central Pair Apparatus Protein)

    i
    Other names: HYDIN, HYDIN Axonemal Central Pair Apparatus Protein, KIAA1864, PPP1R31, CILD5, Protein Phosphatase 1, Regulatory Subunit 31, Hydrocephalus-Inducing Protein Homolog, DKFZp434D0513, HYDIN1, Hydrocephalus Inducing Homolog (Mouse), Hydrocephalus Inducing, HYDIN2
    1year
    The relationship between HYDIN and fallopian tubal cilia loss in patients with epithelial ovarian cancer. (PubMed, Front Oncol)
    We found that the incidence of tubal cilia loss was higher in EOC group with decreased expression of HYDIN compared with the control group (P<0.05). This study suggests that tubal ciliary loss is evident in epithelial fallopian tube carcinoma, and ciliary cells may be involved in the occurrence and development of EOC, and cilia-related gene HYDIN is expected to be a tumor marker for epithelial ovarian cancer.
    Journal • BRCA Biomarker
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    BRCA (Breast cancer early onset) • HYDIN (HYDIN Axonemal Central Pair Apparatus Protein)
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    BRCA mutation
    over2years
    HYDIN mutation status as a potential predictor of immune checkpoint inhibitor efficacy in melanoma. (PubMed, Aging (Albany NY))
    HYDIN mutations are a potential predictive biomarker of ICIs efficacy in melanoma patients.
    Journal • Checkpoint inhibition • PD(L)-1 Biomarker • IO biomarker
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    HYDIN (HYDIN Axonemal Central Pair Apparatus Protein)
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    HYDIN mutation